PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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6SNE	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... 著者 Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. 登録日 2019-08-23 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
5WAW	FcAbVance: Increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery 分子名称: GLYCEROL, ZINC ION, fAb Heavy Chain, ... 著者 Williams, S.P, Reid, R.A, Convery, M. 登録日 2017-06-27 公開日 2017-11-08 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery. Not Published
5Y9C	Crystal structure of HPV58 pentamer in complex with the Fab fragment of antibody A12A3 分子名称: Major capsid protein L1, heavy chain of Fab fragment of antibody A12A3, light chain of Fab fragment of antibody A12A3 著者 Li, S.W, Li, Z.H. 登録日 2017-08-24 公開日 2017-10-25 実験手法 X-RAY DIFFRACTION (3.443 Å) 主引用文献 Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus. MBio, 8, 2017
6G01	Complex of neuraminidase from H1N1 influenza virus with tamiphosphor monomethyl ester 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pachl, P, Pokorna, J. 登録日 2018-03-15 公開日 2019-01-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors. Biochem. J., 475, 2018
1TZH	Crystal Structure of the Fab YADS1 Complexed with h-VEGF 分子名称: Fab YADS1 Heavy Chain, Fab YADS1 Light Chain, Vascular endothelial growth factor A 著者 Fellouse, F.A, Wiesmann, C, Sidhu, S.S. 登録日 2004-07-09 公開日 2004-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition Proc.Natl.Acad.Sci.USA, 101, 2004
1TZI	Crystal Structure of the Fab YADS2 Complexed with h-VEGF 分子名称: Fab YADS2 Heavy Chain, Fab YADS2 Light Chain, Vascular endothelial growth factor A 著者 Fellouse, F.A, Wiesmann, C, Sidhu, S.S. 登録日 2004-07-10 公開日 2004-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition Proc.Natl.Acad.Sci.USA, 101, 2004
3F5V	C2 Crystal form of mite allergen DER P 1 分子名称: CALCIUM ION, Der p 1 allergen, HEXAETHYLENE GLYCOL 著者 Stura, E.A, Minor, W, Chruszcz, M, Saint Remy, J.M. 登録日 2008-11-04 公開日 2009-02-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J.Mol.Biol., 386, 2009
1PJW	Solution Structure of the Domain III of the Japan Encephalitis Virus Envelope Protein 分子名称: envelope protein 著者 Wu, K.P, Wu, C.W, Tsao, Y.P, Lou, Y.C, Lin, C.W. 登録日 2003-06-04 公開日 2003-11-25 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structural Basis of a Flavivirus Recognized by Its Neutralizing Antibody: SOLUTION STRUCTURE OF THE DOMAIN III OF THE JAPANESE ENCEPHALITIS VIRUS ENVELOPE PROTEIN. J.Biol.Chem., 278, 2003
1HEZ	Structure of P. magnus protein L bound to a human IgM Fab. 分子名称: HEAVY CHAIN OF IG, IMIDAZOLE, KAPPA LIGHT CHAIN OF IG, ... 著者 Graille, M, Stura, E.A, Housden, N.G, Bottomley, S.P, Taussig, M.J, Sutton, B.J, Gore, M.G, Charbonnier, J.B. 登録日 2000-11-27 公開日 2001-08-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes Structure, 9, 2001
7T01	SARS-CoV-2 S-RBD + Fab 54042-4 分子名称: 54042-4 Fab - Heavy Chain, 54042-4 Fab - Light Chain, Spike protein S1 著者 Johnson, N.V, Mclellan, J.S. 登録日 2021-11-29 公開日 2022-04-13 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep, 37, 2021
1LMK	THE STRUCTURE OF A BIVALENT DIABODY 分子名称: ANTI-PHOSPHATIDYLINOSITOL SPECIFIC PHOSPHOLIPASE C DIABODY 著者 Williams, R.L. 登録日 1994-08-29 公開日 1995-03-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a diabody, a bivalent antibody fragment. Structure, 2, 1994
6G02	Complex of neuraminidase from H1N1 influenza virus with tamiphosphor omega-azidohexyl ester 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[[(3~{R},4~{R},5~{S})-4-acetamido-5-azanyl-3-pentan-3-yloxy-cyclohexen-1-yl]-oxidanyl-phosphoryl]oxyhexylimino-azanylidene-azanium, ... 著者 Pachl, P, Pokorna, J. 登録日 2018-03-15 公開日 2019-01-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors. Biochem. J., 475, 2018
4JPV	Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-03-19 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.827 Å) 主引用文献 Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell(Cambridge,Mass.), 153, 2013
5ITB	Crystal structure of the anti-RSV F Fab 14N4 分子名称: anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain 著者 Mousa, J.J, Crowe, J.E. 登録日 2016-03-16 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
3L7E	Crystal structure of ANTI-IL-13 antibody C836 分子名称: ACETATE ION, C836 HEAVY CHAIN, C836 LIGHT CHAIN, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2009-12-28 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Antigen recognition by antibody C836 through adjustment of VL/VH packing Acta Crystallogr.,Sect.F, 67, 2011
5X8M	PD-L1 in complex with durvalumab 分子名称: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain 著者 Heo, Y.S, Lee, H.T. 登録日 2017-03-03 公開日 2017-08-16 実験手法 X-RAY DIFFRACTION (2.661 Å) 主引用文献 Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
5X8L	PD-L1 in complex with atezolizumab 分子名称: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain 著者 Heo, Y.S, Lee, H.T. 登録日 2017-03-03 公開日 2017-08-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
5J3D	Crystal structure of human Fab 14N4 in complex with post-fusion RSV F 分子名称: 14N4 heavy chain, 14N4 light chain, Fusion glycoprotein F0 著者 Mousa, J.J, Crowe, J.E. 登録日 2016-03-30 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.077 Å) 主引用文献 Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
6EWB	Crystal structure of GII.4 UNSW 2012 P domain in complex with Fab 10E9 分子名称: 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... 著者 Koromyslova, A.D, Hansman, G.S. 登録日 2017-11-03 公開日 2018-11-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Human Norovirus Neutralized by a Monoclonal Antibody Targeting the Histo-Blood Group Antigen Pocket. J.Virol., 93, 2019
6MSY	Anti-HIV-1 Fab Fab 2G12 + Man4 re-refinement 分子名称: ACETATE ION, Fab 2G12, light chain, ... 著者 Calarese, D.A, Stanfield, R.L, Wilson, I.A. 登録日 2018-10-18 公開日 2018-11-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6MNF	Anti-HIV-1 Fab 2G12 + Man8 re-refinement 分子名称: Fab 2G12, light chain, Fab 2g12, ... 著者 Calarese, D.A, Stanfield, R.L, Wilson, I.A. 登録日 2018-10-01 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.758 Å) 主引用文献 Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
4I18	Crystal structure of human prolactin receptor complexed with Fab fragment 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Duguid, E.M, Mukherjee, S, Kouadio, J.L. 登録日 2012-11-20 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.238 Å) 主引用文献 Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling. Cell Commun Signal, 13, 2015
6N5D	Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope 分子名称: Hemagglutinin, antibody heavy chain, antibody light chain 著者 Bajic, G, Schmidt, A.G. 登録日 2018-11-21 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. Cell Host Microbe, 25, 2019
6NFC	BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2018-12-19 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
3U0W	AD related murine antibody Fragment 分子名称: Fab Heavy Chain, Ig gamma-1 chain C region, Fab Light Chain, ... 著者 Miles, L.A, Crespi, G.A.N, Parker, M.W. 登録日 2011-09-29 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of an AD related antibody To be Published

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