1HEZ

Structure of P. magnus protein L bound to a human IgM Fab.

Summary for 1HEZ

• Entry DOI: 10.2210/pdb1hez/pdb
• Descriptor: KAPPA LIGHT CHAIN OF IG, HEAVY CHAIN OF IG, PROTEIN L, ... (5 entities in total)
• Functional Keywords: antibody, superantigen
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 5
• Total formula weight: 102220.67

Authors

Graille, M.,Stura, E.A.,Housden, N.G.,Bottomley, S.P.,Taussig, M.J.,Sutton, B.J.,Gore, M.G.,Charbonnier, J.B. (deposition date: 2000-11-27, release date: 2001-08-10, Last modification date: 2024-11-20)

Primary citation

Graille, M.,Stura, E.A.,Housden, N.G.,Beckingham, J.A.,Bottomley, S.P.,Beale, D.,Taussig, M.J.,Sutton, B.J.,Gore, M.G.,Charbonnier, J.B.
Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9:679-, 2001

PubMed Abstract: Peptostreptococcus magnus protein L (PpL) is a multidomain, bacterial surface protein whose presence correlates with virulence. It consists of up to five homologous immunoglobulin binding domains that interact with the variable (VL) regions of kappa light chains found on two thirds of mammalian antibodies.

PubMed: 11587642
DOI: 10.1016/S0969-2126(01)00630-X

Experimental method

X-RAY DIFFRACTION (2.7 Å)