2PS6
 
 | | N225D/S229T trichodiene synthase | | 分子名称: | 1,2-ETHANEDIOL, Trichodiene synthase | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
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2CG4
 | | Structure of E.coli AsnC | | 分子名称: | ASPARAGINE, MAGNESIUM ION, REGULATORY PROTEIN ASNC | | 著者 | Thaw, P, Sedelnikova, S.E, Muranova, T, Wiese, S, Ayora, S, Alonso, J.C, Brinkman, A.B, Akerboom, J, van der Oost, J, Rafferty, J.B. | | 登録日 | 2006-02-27 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family.
Nucleic Acids Res., 34, 2006
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4N6N
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1Y52
 | | structure of insect cell (Baculovirus) expressed AVR4 (C122S)-biotin complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin-related protein 4/5, BIOTIN | | 著者 | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | | 登録日 | 2004-12-02 | | 公開日 | 2005-05-24 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
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6TCX
 | | Papain bound to a natural cysteine protease inhibitor from Streptomyces mobaraensis | | 分子名称: | (2~{R})-2-[[(1~{S})-1-[(6~{S})-2-azanyl-1,4,5,6-tetrahydropyrimidin-6-yl]-2-[[(2~{S})-3-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]amino]-2-oxidanylidene-ethyl]carbamoylamino]-3-(4-hydroxyphenyl)propanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Papain | | 著者 | Kraemer, A, Juettner, N.E, Fuchsbauer, H.-L, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2019-11-06 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway.
J.Nat.Prod., 83, 2020
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2PS4
 | | N225D trichodiene synthase | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Trichodiene synthase | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
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2PS5
 | | N225D Trichodiene Synthase: Complex With Mg and Pyrophosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
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4TUA
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4RLK
 | | Crystal structure of Z. mays CK2alpha in complex with the ATP-competitive inhibitor 4-[(E)-(fluoren-9-ylidenehydrazinylidene)-methyl] benzoate | | 分子名称: | 4-[(E)-(9H-fluoren-9-ylidenehydrazinylidene)methyl]benzoic acid, ACETATE ION, Casein kinase II subunit alpha, ... | | 著者 | Guerra, B, Rasmussen, T.D.L, Schnitzler, A, Jensen, H.H, Boldyreff, B.S, Miyata, Y, Marcussen, N, Niefind, K, Issinger, O.G. | | 登録日 | 2014-10-17 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Protein kinase CK2 inhibition is associated with the destabilization of HIF-1 alpha in human cancer cells.
Cancer Lett, 356, 2015
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7W6Y
 | | Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1 | | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Anti sigma-E protein, RseA, ... | | 著者 | Imaizumi, Y, Takanuki, K, Nogi, T. | | 登録日 | 2021-12-02 | | 公開日 | 2022-09-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
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4EHM
 | | RabGGTase in complex with covalently bound Psoromic acid | | 分子名称: | 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ... | | 著者 | Guo, Z, Deraeve, C, Bon, R.S, Alexandrov, K, Waldmann, H, Wu, Y.W, Goody, R.S, Blankenfeldt, W. | | 登録日 | 2012-04-02 | | 公開日 | 2012-05-30 | | 最終更新日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase
J.Am.Chem.Soc., 134, 2012
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5C0U
 | | Crystal structure of the copper-bound form of MerB mutant D99S | | 分子名称: | Alkylmercury lyase, BROMIDE ION, COPPER (II) ION | | 著者 | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | | 登録日 | 2015-06-12 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
Biochemistry, 55, 2016
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1U98
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2AI9
 | | S.aureus Polypeptide Deformylase | | 分子名称: | NICKEL (II) ION, Peptide deformylase, SULFATE ION | | 著者 | Smith, K.J, Petit, C.M, Aubart, K, Smyth, M, McManus, E, Jones, J, Fosberry, A, Lewis, C, Lonetto, M, Christensen, S.B. | | 登録日 | 2005-07-29 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Variation and inhibitor binding in polypeptide deformylase from four different bacterial species.
Protein Sci., 12, 2003
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2AJH
 | | Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine | | 分子名称: | Leucyl-tRNA synthetase, METHIONINE | | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | | 登録日 | 2005-08-02 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination
Biochem.J., 394, 2006
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1DQK
 | | CRYSTAL STRUCTURE OF SUPEROXIDE REDUCTASE IN THE REDUCED STATE AT 2.0 ANGSTROMS RESOLUTION | | 分子名称: | FE (II) ION, SUPEROXIDE REDUCTASE | | 著者 | Yeh, A.P, Hu, Y, Jenney Jr, F.E, Adams, M.W.W, Rees, D.C. | | 登録日 | 2000-01-04 | | 公開日 | 2000-05-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states.
Biochemistry, 39, 2000
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1SO4
 | | Crystal structure of K64A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate | | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION | | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | | 登録日 | 2004-03-12 | | 公開日 | 2004-06-08 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
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3T91
 | | Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis | | 分子名称: | MANGANESE (II) ION, Stage II sporulation protein E, alpha-D-mannopyranose, ... | | 著者 | Levdikov, V.M, Blagova, E.V, Wilkinson, A.J. | | 登録日 | 2011-08-02 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structure of the phosphatase domain of the cell fate determinant SpoIIE from Bacillus subtilis.
J.Mol.Biol., 415, 2012
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2P14
 | | Crystal structure of small subunit (R.BspD6I2) of the heterodimeric restriction endonuclease R.BspD6I | | 分子名称: | GLYCEROL, Heterodimeric restriction endonuclease R.BspD6I small subunit, SULFATE ION | | 著者 | Kachalova, G.S, Bartunik, H.D, Artyukh, R.I, Rogulin, E.A, Yunusova, A.K, Zheleznaya, L.A, Matvienko, N.I. | | 登録日 | 2007-03-02 | | 公開日 | 2008-03-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit.
J.Mol.Biol., 384, 2008
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3P7I
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2PS8
 | | Y295F Trichodiene Synthase: Complex With Mg and Pyrophosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
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7FCR
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2A8V
 | | RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX | | 分子名称: | 5'-R(P*CP*CP*C)-3', 5'-R(P*CP*CP*CP*CP*CP*C)-3', RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR | | 著者 | Bogden, C.E, Fass, D, Bergman, N, Nichols, M.D, Berger, J.M. | | 登録日 | 1998-11-08 | | 公開日 | 1999-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999
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1HBR
 | | R-STATE FORM OF CHICKEN HEMOGLOBIN D | | 分子名称: | PROTEIN (HEMOGLOBIN D), PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Knapp, E, Oliveira, M.A, Xie, Q, Ernst, S.R, Riggs, A.F, Hackert, M.L. | | 登録日 | 1998-12-06 | | 公開日 | 1999-03-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structural and functional analysis of the hemoglobin D component from chicken.
J.Biol.Chem., 274, 1999
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2FLO
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