2PS6

N225D/S229T trichodiene synthase

Summary for 2PS6

Entry DOI	10.2210/pdb2ps6/pdb
Related	1JFA 1KIY 1YJ4 2AEK 2PS4 2PS7
Descriptor	Trichodiene synthase, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	terpenoid synthase fold, site-directed mutagenesis, nse/dte motif, magnesium, ethylene glycol, lyase
Biological source	Fusarium sporotrichioides
Total number of polymer chains	2
Total formula weight	88255.36
Authors	Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2007-05-04, release date: 2007-12-18, Last modification date: 2023-08-30)
Primary citation	Vedula, L.S.,Jiang, J.,Zakharian, T.,Cane, D.E.,Christianson, D.W. Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469:184-194, 2008 Cited by PubMed: 17996718 DOI: 10.1016/j.abb.2007.10.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation