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4I3S
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BU of 4i3s by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21
分子名称: CALCIUM ION, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
著者Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
登録日2012-11-26
公開日2013-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
7T9J
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BU of 7t9j by Molmil
Cryo-EM structure of the SARS-CoV-2 Omicron spike protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Tuttle, K.S, Subramaniam, S.
登録日2021-12-19
公開日2021-12-29
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex.
Science, 375, 2022
7T9K
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BU of 7t9k by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
著者Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Tuttle, K.S, Subramaniam, S.
登録日2021-12-19
公開日2021-12-29
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex.
Science, 375, 2022
3NN8
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BU of 3nn8 by Molmil
Crystal structure of engineered antibody fragment based on 3D5
分子名称: Engineered scFv
著者Lieberman, R.L, Maynard, J.A, Drury, J.E, Pai, J, Culver, J.A.
登録日2010-06-23
公開日2011-06-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Peptide-binding single chain Antibody fragment (SCFV) chaperones for protein co-crystallization
To be Published
7T9L
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BU of 7t9l by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein
著者Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Tuttle, K.S, Subramaniam, S.
登録日2021-12-19
公開日2021-12-29
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex.
Science, 375, 2022
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-11-14
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.0041 Å)
主引用文献A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
2LP7
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BU of 2lp7 by Molmil
Structure of gp41-M-MAT, a membrane associated MPER trimer from HIV-1 gp41.
分子名称: Envelope glycoprotein
著者Reardon, P.N.
登録日2012-02-03
公開日2013-02-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
5WAV
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BU of 5wav by Molmil
Fc AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Immunoglobulin gamma-1 heavy chain,Immunoglobulin gamma-1 heavy chain
著者Williams, S.P, Reid, R.A, Convery, M.A.
登録日2017-06-27
公開日2017-11-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
To Be Published
8JIO
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BU of 8jio by Molmil
XBB spike protein (S) in complex with monoclonal antibody 6I18
分子名称: 6I18 heavy chain, 6I18 light chain, Spike glycoprotein
著者Ma, Y, Mao, Q, Wang, Y, Zhang, Z.
登録日2023-05-27
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of XBB spike protein (S) in complex with monoclonal antibody 6I18 at 3.30 Angstroms resolution.
To Be Published
2M7W
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BU of 2m7w by Molmil
Independently verified structure of gp41-M-MAT, a membrane associated MPER trimer from HIV-1 gp41
分子名称: Envelope glycoprotein
著者Martin, J.W, Reardon, P.N, Sage, H.S, Moses, D.S, Munir, A.S, Haynes, B.F, Spicer, L.D, Donald, B.R.
登録日2013-05-01
公開日2013-05-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
5IHZ
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BU of 5ihz by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-01
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5WYM
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BU of 5wym by Molmil
Crystal structure of an anti-connexin26 scFv
分子名称: anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain
著者Li, S, Xu, L.
登録日2017-01-13
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
Front Mol Neurosci, 10, 2017
8KGZ
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BU of 8kgz by Molmil
Crystal structure of single-chain Fv antibody against antigen peptide from SARS-CoV2 S-spike protein
分子名称: Thioredoxin 1,scFv
著者Ma, Q.Q, Zhang, B.L, Cheng, X.Y, Huang, Y.Q, Su, Z.D.
登録日2023-08-20
公開日2023-11-08
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of sheep scFv antibody against an antigen peptide of SARS-CoV2 S-spike protein
To Be Published
5IJK
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BU of 5ijk by Molmil
Crystal structure of anti-gliadin 1002-1E03 Fab fragment in complex of peptide PLQPEQPFP
分子名称: 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-02
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
7M8L
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BU of 7m8l by Molmil
EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein 1, ...
著者Murin, C.D, Ward, A.B.
登録日2021-03-30
公開日2021-11-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Pan-ebolavirus protective therapy by two multifunctional human antibodies.
Cell, 184, 2021
5IFJ
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BU of 5ifj by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-02-26
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
1YEH
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BU of 1yeh by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT
分子名称: FAB FRAGMENT, ZINC ION
著者Gigant, B, Knossow, M.
登録日1997-05-29
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
7REW
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BU of 7rew by Molmil
Crystal Structure of IL-13 in complex with MMAb3 Fab
分子名称: IL13, anti-cyno interleukin 13 Fab heavy chain, anti-cyno interleukin 13 Fab light chain
著者Sudom, A, Min, X.
登録日2021-07-13
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation.
J.Biol.Chem., 298, 2022
3N9G
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BU of 3n9g by Molmil
Crystal structure of the Fab fragment of the human neutralizing anti-West Nile Virus MAb CR4354
分子名称: Fab fragment of MAb CR4354, heavy chain, light chain
著者Kaufmann, B, Rossmann, M.G.
登録日2010-05-29
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.434 Å)
主引用文献Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.
Proc.Natl.Acad.Sci.USA, 107, 2010
5SY8
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BU of 5sy8 by Molmil
Crystal structure of the complex of 10E8 Fab light chain mutant1 and T117v2 HIV-1 MPER scaffold
分子名称: 10E8 EPITOPE SCAFFOLD T117v2, 10E8 FAB HEAVY CHAIN, 10E8 FAB LIGHT CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-08-10
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
4ODX
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BU of 4odx by Molmil
4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
分子名称: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain
著者Finton, K.A.K.
登録日2014-01-10
公開日2014-10-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
5IG7
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BU of 5ig7 by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPQQPFP
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-02-27
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
2ARJ
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BU of 2arj by Molmil
CD8alpha-alpha in complex with YTS 105.18 Fab
分子名称: T-cell surface glycoprotein CD8 alpha chain, YTS 105.18 antigen binding region Heavy chain, YTS 105.18 antigen binding region Light chain
著者Shore, D.A, Teyton, L, Dwek, R.A, Rudd, P.M, Wilson, I.A.
登録日2005-08-19
公開日2006-05-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
J.Mol.Biol., 358, 2006
5Y9F
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BU of 5y9f by Molmil
Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10
分子名称: Major capsid protein L1, heavy chain of Fab fragment of antibody 28F10, light chains of Fab fragment of antibody 28F10
著者Li, S.W, Li, Z.H.
登録日2017-08-24
公開日2017-10-25
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5IK3
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BU of 5ik3 by Molmil
Crystal structure of anti-gliadin 1002-1E03 Fab fragment
分子名称: 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-03
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017

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