7M8L

EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs

Summary for 7M8L

• Entry DOI: 10.2210/pdb7m8l/pdb
• EMDB information: 23719
• Descriptor: Virion spike glycoprotein 1, rEBOV-442 Fab heavy chain, rEBOV-442 Fab light chain, ... (9 entities in total)
• Functional Keywords: ebolavirus, ebov, antibody, antibody therapeutic, mabs, filovirus, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Ebola virus; More
• Total number of polymer chains: 18
• Total formula weight: 468888.36

Authors

Murin, C.D.,Ward, A.B. (deposition date: 2021-03-30, release date: 2021-11-10)

• Primary citation: Gilchuk, P.,Murin, C.D.,Cross, R.W.,Ilinykh, P.A.,Huang, K.,Kuzmina, N.,Borisevich, V.,Agans, K.N.,Geisbert, J.B.,Zost, S.J.,Nargi, R.S.,Sutton, R.E.,Suryadevara, N.,Bombardi, R.G.,Carnahan, R.H.,Bukreyev, A.,Geisbert, T.W.,Ward, A.B.,Crowe Jr., J.E.; Pan-ebolavirus protective therapy by two multifunctional human antibodies.; Cell, 184:5593-5607.e18, 2021; PubMed: 34715022; DOI: 10.1016/j.cell.2021.09.035

Experimental method

ELECTRON MICROSCOPY (3.9 Å)