PDB: 224931 件ウェブページステータス検索Chemie searchBIRD

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2G8N	Structure of hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy 分子名称: (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Gee, C.L, Martin, J.L. 登録日 2006-03-02 公開日 2006-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Comparison of the Binding of 3-Fluoromethyl-7-sulfonyl-1,2,3,4-tetrahydroisoquinolines with Their Isosteric Sulfonamides to the Active Site of Phenylethanolamine N-Methyltransferase J.Med.Chem., 49, 2006
2G8Q	The crystal structure of RNase A from monoclinic crystals at 100 K 分子名称: Ribonuclease pancreatic 著者 Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. 登録日 2006-03-03 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal. Bioorg.Med.Chem., 14, 2006
2G8R	The crystal structure of the RNase A- 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine complex 分子名称: 1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARABINOFURANOSYL]PYRIMIDINE-2,4(1H,3H)-DIONE, Ribonuclease pancreatic 著者 Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. 登録日 2006-03-03 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal. Bioorg.Med.Chem., 14, 2006
2G8S	Crystal structure of the soluble Aldose sugar dehydrogenase (Asd) from Escherichia coli in the apo-form 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glucose/sorbosone dehydrogenases, ... 著者 Southall, S.M, Doel, J.J, Richardson, D.J, Oubrie, A. 登録日 2006-03-03 公開日 2006-08-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Soluble Aldose Sugar Dehydrogenase from Escherichia coli: A HIGHLY EXPOSED ACTIVE SITE CONFERRING BROAD SUBSTRATE SPECIFICITY. J.Biol.Chem., 281, 2006
2G8T	Indole-amidine Complexes with Bovine Trypsin 分子名称: 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin, ... 著者 Kline, A.D, Briggs, S.L, Subramaniam, S. 登録日 2006-03-03 公開日 2006-09-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Ligand Epitoping By Proton NMR Chemical Shift Differences To be published
2G8U	B. halodurans RNase H catalytic domain D132N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site) 分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ... 著者 Nowotny, M, Yang, W. 登録日 2006-03-03 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8V	B. halodurans RNase H catalytic domain E188A mutant in complex with Mg2+ and RNA/DNA hybrid (reaction product) 分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', ETHANOL, ... 著者 Nowotny, M, Yang, W. 登録日 2006-03-03 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8W	B. halodurans RNase H catalytic domain E188A mutant in complex with Ca2+ and RNA/DNA hybrid 分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', CALCIUM ION, ... 著者 Nowotny, M, Yang, W. 登録日 2006-03-03 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
2G8X	Escherichia coli Y209W apoprotein 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CARBONATE ION, PHOSPHATE ION, ... 著者 Lee, T.T, Finer-Moore, J.S, Stroud, R.M. 登録日 2006-03-03 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 The role of protein dynamics in thymidylate synthase catalysis: Variants of conserved dUMP-binding Tyr-261 TO BE PUBLISHED
2G8Y	The structure of a putative malate/lactate dehydrogenase from E. coli. 分子名称: 1,2-ETHANEDIOL, Malate/L-lactate dehydrogenases, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-03-03 公開日 2006-04-25 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The structure of a putative malate/lactate dehydrogenase from E. coli. To be Published
2G8Z	Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution 分子名称: (TRP)(PRO)(TRP), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, ... 著者 Ethayathulla, A.S, Srivastava, D.B, Kumar, J, Somvanshi, R.K, Sharma, S, Singh, T.P. 登録日 2006-03-04 公開日 2006-04-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution To be Published
2G91	Crystal Structure Analysis of the an RNA nonamer r(GGUGCGC)d(BrC)r(C) 分子名称: 5'-R(*GP*GP*UP*GP*CP*GP*CP*(CBR)P*C-3', MAGNESIUM ION 著者 Shi, K, Pan, B, Sundaralingam, M. 登録日 2006-03-04 公開日 2007-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of an RNA nonamer r(GGUGCGC)d(BrC)r(C) at 1.5 A resolution To be Published
2G92	Crystal Structure Analysis of the RNA Dodecamer CGC-(NF2)-AAUUAGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2) 分子名称: 5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*AP*GP*CP*G)-3' 著者 Egli, M, Li, F. 登録日 2006-03-04 公開日 2006-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. Acs Chem.Biol., 1, 2006
2G93	Ligand recognition site in C-lobe of lactoferrin: Crystal structure of the complex of C-lobe of bovine lactoferrin with methyl alpha-D-mannopyranoside at 1.9 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... 著者 Singh, N, Sharma, S, Singh, T.P. 登録日 2006-03-05 公開日 2006-03-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand recognition site in C-lobe of lactoferrin: Crystal structure of the complex of C-lobe of bovine lactoferrin with methyl alpha-D-mannopyranoside at 1.9 A resolution To be Published
2G94	Crystal structure of beta-secretase bound to a potent and highly selective inhibitor. 分子名称: Beta-secretase 1, N~2~-[(2R,4S,5S)-5-{[N-{[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHOXY]CARBONYL}-3-(METHYLSULFONYL)-L-ALANYL]AMINO}-4-HYDROXY-2,7-DIMETHYLOCTANOYL]-N-ISOBUTYL-L-VALINAMIDE 著者 Hong, L, Ghosh, A, Tang, J. 登録日 2006-03-05 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J.Am.Chem.Soc., 128, 2006
2G95	Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase 分子名称: Nicotinamide phosphoribosyltransferase 著者 Kim, M.-K, Eom, S.H. 登録日 2006-03-05 公開日 2006-08-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866 J.Mol.Biol., 362, 2006
2G96	Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with Niconamide Mononucleotide 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide phosphoribosyltransferase 著者 Eom, S.H, Kim, M.-K. 登録日 2006-03-05 公開日 2006-08-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866 J.Mol.Biol., 362, 2006
2G97	Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase 著者 Kim, M.-K, Eom, S.H. 登録日 2006-03-05 公開日 2006-08-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866 J.Mol.Biol., 362, 2006
2G98	human gamma-D-crystallin 分子名称: Gamma crystallin D 著者 Kmoch, S, Brynda, J, Awsav, B, Bezouska, K, Novak, P, Rezacova, P. 登録日 2006-03-06 公開日 2006-05-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography. Hum.Mol.Genet., 12, 2000
2G99	Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 分子名称: Histone H3, WD-repeat protein 5 著者 Chai, J, Han, Z, Wang, H, Shen, Y. 登録日 2006-03-06 公開日 2006-09-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 To be published
2G9A	Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 分子名称: Histone H3, WD-repeat protein 5 著者 Chai, J, Han, Z, Wang, H, Shen, Y. 登録日 2006-03-06 公開日 2006-09-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 To be published
2G9B	NMR solution structure of CA2+-loaded calbindin D28K 分子名称: Calbindin 著者 Kojetin, D.J, Venters, R.A, Kordys, D.R, Thompson, R.J, Kumar, R, Cavanagh, J. 登録日 2006-03-06 公開日 2006-07-04 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure, binding interface and hydrophobic transitions of Ca(2+)-loaded calbindin-D(28K). Nat.Struct.Mol.Biol., 13, 2006
2G9C	Modified pyrimidines Specifically bind the purine riboswitch 分子名称: ACETATE ION, COBALT HEXAMMINE(III), PYRIMIDINE-2,4,6-TRIAMINE, ... 著者 Gilbert, S.D, Mediatore, S.J, Batey, R.T. 登録日 2006-03-06 公開日 2006-11-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Modified pyrimidines specifically bind the purine riboswitch. J.Am.Chem.Soc., 128, 2006
2G9D	Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20 分子名称: Succinylglutamate desuccinylase 著者 Zhou, W, Jayaraman, S, Forouhar, F, Conover, K, Rong, X, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2006-03-06 公開日 2006-04-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20. To be Published
2G9E	Protonation-mediated structural flexibility in the F conjugation regulatory protein, TRAM 分子名称: Protein traM 著者 Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N. 登録日 2006-03-06 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM. Embo J., 25, 2006

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