PDB: 214399 件ウェブページステータス検索Chemie searchBIRD

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5NT7	Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of Vasa 分子名称: ATP-dependent RNA helicase vasa, isoform A, Maternal effect protein oskar 著者 Jeske, M, Ephrussi, A, Mueller, C.W. 登録日 2017-04-27 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage. Genes Dev., 31, 2017
8A5M	TRIM7 PRYSPRY in complex with a MNV1-NS6 peptide LEALEFQ 分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS6 peptide LEALEFQ, PHOSPHATE ION 著者 Luptak, J. 登録日 2022-06-15 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.918 Å) 主引用文献 TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
5OU0	Crystal structure of human AKR1B1 complexed with NADP+ and compound 37 分子名称: 2-[5-(4-chlorophenyl)-3-methyl-1-oxidanylidene-pyrimido[4,5-c]quinolin-2-yl]ethanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Metwally, K, Podjarny, A. 登録日 2017-08-23 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.94 Å) 主引用文献 Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. Eur J Med Chem, 152, 2018
2WQL	CRYSTAL STRUCTURE OF THE MAJOR CARROT ALLERGEN DAU C 1 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAJOR ALLERGEN DAU C 1, ... 著者 Markovic-Housley, Z, Basle, A, Padavattan, S, Hoffmann-Sommergruber, K, Schirmer, T. 登録日 2009-08-24 公開日 2009-09-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the Major Carrot Allergen Dau C 1. Acta Crystallogr.,Sect.D, 65, 2009
7Y4T	Crystal structure of cMET kinase domain bound by compound 9I 分子名称: 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one, Hepatocyte growth factor receptor 著者 Qu, L.Z, Chen, Y.H. 登録日 2022-06-16 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
7Y4U	Crystal structure of cMET kinase domain bound by compound 9Y 分子名称: Hepatocyte growth factor receptor, ~{N}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide 著者 Qu, L.Z, Chen, Y.H. 登録日 2022-06-16 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
5YZG	The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. 登録日 2017-12-14 公開日 2018-08-08 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure of a human catalytic step I spliceosome Science, 359, 2018
4ASX	Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C 分子名称: 1,2-ETHANEDIOL, 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2H-pyrido[3,4-b]indol-1-one, ACTIVIN RECEPTOR TYPE-2A 著者 Williams, E, Chaikuad, A, Canning, P, Kochan, G, Mahajan, P, Cooper, C.D.O, Beltrami, A, Krojer, T, Pohl, B, Bracher, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A. 登録日 2012-05-03 公開日 2012-05-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of Activin Receptor Type-Iia (Acvr2A) Kinase Domain in Complex with a Beta- Carboline Inhibitor To be Published
6E1C	Crystal structure of a MauG-like protein associated with microbial copper homeostasis 分子名称: CALCIUM ION, Di-heme enzyme, HEME C 著者 Dassama, L.M.K, Rosenzweig, A.C. 登録日 2018-07-09 公開日 2019-07-17 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (2.617 Å) 主引用文献 MbnH is a diheme MauG-like protein associated with microbial copper homeostasis. J.Biol.Chem., 294, 2019
1O8F	Pectate Lyase C from Erwinia Chrysanthemi at pH 9.5 with 30mM Ca2+ 分子名称: CALCIUM ION, PECTATE LYASE C 著者 Herron, S.R, Jurnak, F.A. 登録日 2002-11-27 公開日 2003-01-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization and Implications of Ca2+ Binding to Pectate Lyase C J.Biol.Chem., 278, 2003
7K6D	SARS-CoV-2 Main Protease Co-Crystal Structure with Telaprevir Determined from Crystals Grown with 40 nL Acoustically Ejected Mpro Droplets at 1.48 A Resolution (Cryo-protected) 分子名称: (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Kreitler, D.F, Andi, B, Kumaran, D, Soares, A.S, Shi, W, Jakoncic, J, Fuchs, M.R, Keereetaweep, J, Shanklin, J, McSweeney, S. 登録日 2020-09-19 公開日 2020-09-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease. Sci Rep, 12, 2022
5IR6	The structure of bd oxidase from Geobacillus thermodenitrificans 分子名称: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ... 著者 Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H. 登録日 2016-03-12 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases. Science, 352, 2016
6E3F	The structure of the C-terminal domains (C123) of Streptococcus intermedius antigen I/II (Pas) 分子名称: CALCIUM ION, Probable cell-surface antigen I/II 著者 Schormann, N, Deivanayagam, C. 登録日 2018-07-13 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-Function Characterization of Streptococcus intermedius Surface Antigen Pas. J.Bacteriol., 203, 2021
1C86	CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B (R47V,D48N) COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID 分子名称: 2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID, PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) 著者 Iversen, L.F, Andersen, H.S, Mortensen, S.B, Moller, N.P. 登録日 2000-04-16 公開日 2000-05-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J.Biol.Chem., 275, 2000
4PA6	Structure of NavMS pore and C-terminal domain crystallised in the presence of channel blocking compound 分子名称: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... 著者 Naylor, C.E, Bagneris, C, Wallace, B.A. 登録日 2014-04-07 公開日 2014-06-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism. Proc.Natl.Acad.Sci.USA, 111, 2014
6ROA	Crystal structure of V57G mutant of human cystatin C 分子名称: Cystatin-C 著者 Orlikowska, M, Behrendt, I, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. 登録日 2019-05-10 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution. Febs J., 287, 2020
6M5Z	Catalytic domain of GH30 xylanase C from Talaromyces cellulolyticus 分子名称: ACETATE ION, GH30 Xylanase C, GLYCEROL, ... 著者 Nakamichi, Y, Watanabe, M, Inoue, H. 登録日 2020-03-12 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of GH30-7 endoxylanase C from the filamentous fungus Talaromyces cellulolyticus. Acta Crystallogr.,Sect.F, 76, 2020
5ITH	TIA-1 RRM2 recognition of target oligonucleotide 分子名称: DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3'), Nucleolysin TIA-1 isoform p40 著者 Waris, S, Wilce, J.A, Wilce, M.C. 登録日 2016-03-16 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 TIA-1 RRM23 binding and recognition of target oligonucleotides. Nucleic Acids Res., 45, 2017
6MFT	Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Weidle, C, Pancera, M, Stamatatos, L, Gray, M. 登録日 2018-09-12 公開日 2018-11-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.315 Å) 主引用文献 Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
5IVX	Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... 著者 Natarajan, K, Jiang, J, Margulies, D. 登録日 2016-03-21 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An allosteric site in the T-cell receptor C beta domain plays a critical signalling role. Nat Commun, 8, 2017
6LOE	Cryo-EM structure of the dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii 分子名称: Cytochrome c domain-containing protein, FE3-S4 CLUSTER, Fe-S-cluster-containing hydrogenase components 1-like protein, ... 著者 Shi, Y, Xin, Y.Y, Wang, C, Blankenship, R.E, Sun, F, Xu, X.L. 登録日 2020-01-05 公開日 2020-11-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii . Sci Adv, 6, 2020
3IDB	Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S. 登録日 2009-07-20 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. J.Mol.Biol., 393, 2009
7K6E	SARS-CoV-2 Main Protease Co-Crystal Structure with Telaprevir Determined from Crystals Grown with 40 nL Acoustically Ejected Mpro Droplets at 1.63 A Resolution (Direct Vitrification) 分子名称: (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Kreitler, D.F, Andi, B, Kumaran, D, Soares, A.S, Shi, W, Jakoncic, J, Fuchs, M.R, Keereetaweep, J, Shanklin, J, McSweeney, S. 登録日 2020-09-19 公開日 2020-09-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease. Sci Rep, 12, 2022
1AOD	PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM LISTERIA MONOCYTOGENES 分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C 著者 Heinz, D.W, Moser, J. 登録日 1997-07-02 公開日 1998-01-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the phosphatidylinositol-specific phospholipase C from the human pathogen Listeria monocytogenes. J.Mol.Biol., 273, 1997
4PA7	Structure of NavMS pore and C-terminal domain crystallised in presence of channel blocking compound 分子名称: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... 著者 Naylor, C.E, Bagneris, C, Wallace, B.A. 登録日 2014-04-07 公開日 2014-06-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism. Proc.Natl.Acad.Sci.USA, 111, 2014

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