PDB: 214399 件ウェブページステータス検索Chemie searchBIRD

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5MXY	KustC0563 c-type cytochrome 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cytochrome c-552 Ks_3358, ... 著者 Mohd, A, Barends, T. 登録日 2017-01-25 公開日 2018-02-14 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Specificity of Small c -Type Cytochromes in Anaerobic Ammonium Oxidation. Acs Omega, 6, 2021
5MY4	Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with human Abeta-pE3-12PEGb 分子名称: Fab c#17 heavy chain, Fab c#17 light chain, Pyroglutamate-Abeta pE3-12-PEGb 著者 Parthier, C, Piechotta, A, Stubbs, M.T. 登録日 2017-01-25 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.211 Å) 主引用文献 Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy. J. Biol. Chem., 292, 2017
5VN9	Structure of bacteriorhodopsin from crystals grown at 4 deg C using GlyNCOC15+4 as an LCP host lipid 分子名称: Bacteriorhodopsin 著者 Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. 登録日 2017-04-28 公開日 2017-07-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.594 Å) 主引用文献 Chemically Stable Lipids for Membrane Protein Crystallization. Cryst Growth Des, 17, 2017
7LGR	Streptococcus mutans Collagen binding Protein CNM - N2 Domain 分子名称: Collagen-binding adhesin 著者 Schormann, N, Deivanayagam, C. 登録日 2021-01-20 公開日 2022-01-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Streptococcus mutans Collagen binding Protein CNM - Structural and Functional Analysis of the C-terminal N2 Domain To Be Published
6DF4	TAF1-BD2 in complex with Cpd8 (6-(but-3-en-1-yl)-4-(3-(morpholine-4-carbonyl)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one) 分子名称: 6-(but-3-en-1-yl)-4-[3-(morpholine-4-carbonyl)phenyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit 著者 Murray, J.M, Tang, Y. 登録日 2018-05-14 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J. Med. Chem., 61, 2018
6DF7	TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one) 分子名称: 6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit 著者 Murray, J.M. 登録日 2018-05-14 公開日 2018-11-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J. Med. Chem., 61, 2018
5K64	Crystal structure of VEGF binding IgG1-Fc (Fcab 448) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Humm, A, Lobner, E, Kitzmuller, M, Mlynek, G, Obinger, C, Djinovic-Carugo, K. 登録日 2016-05-24 公開日 2017-09-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex. MAbs, 9, 2017
8SM9	Air-oxidized C. fi TruffO expressed from M9 minimal medium supplemented with Fe 分子名称: Amidohydrolase 2, FE (III) ION 著者 Liu, C, Rittle, J. 登録日 2023-04-25 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Bioinformatic Discovery of a Cambialistic Monooxygenase. J.Am.Chem.Soc., 146, 2024
3LRR	Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA 分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION 著者 Li, P. 登録日 2010-02-11 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain. Structure, 18, 2010
5VX6	Structure of Bacillus subtilis Inhibitor of motility (MotI/DgrA) 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein YpfA 著者 Subramanian, S, Dann III, C. 登録日 2017-05-23 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.197 Å) 主引用文献 MotI (DgrA) acts as a molecular clutch on the flagellar stator protein MotA inBacillus subtilis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DJR	Full-length human TRPC3 in GDN 分子名称: Transient Receptor Potential Cation Channel Subfamily C Member 3 著者 Sierra-Valdez, F.J, Azumaya, C.M, Nakagawa, T, Cordero-Morales, J.F. 登録日 2018-05-26 公開日 2018-08-29 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating. J. Biol. Chem., 293, 2018
5YTF	Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
1N31	Structure of A Catalytically Inactive Mutant (K223A) of C-DES with a Substrate (Cystine) Linked to the Co-Factor 分子名称: CYSTEINE, L-cysteine/cystine lyase C-DES, POTASSIUM ION, ... 著者 Kaiser, J.T, Bruno, S, Clausen, T, Huber, R, Schiaretti, F, Mozzarelli, A, Kessler, D. 登録日 2002-10-25 公開日 2003-01-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Snapshots of the Cystine Lyase "C-DES" during Catalysis: Studies in Solution and in the Crystalline State J.Biol.Chem., 278, 2003
7JWE	Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma 分子名称: Gedatolisib, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Burke, J.E, Rathinaswamy, M.K, Harris, N.J. 登録日 2020-08-25 公開日 2021-03-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Disease related mutations in PI3K gamma disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. Elife, 10, 2021
8TB5	TYK2 JH2 bound to Compound7 分子名称: ACETATE ION, N-{(3P)-3-[3-(dimethylsulfamoyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-5-yl}cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2 著者 Argiriadi, M.A, Van Epps, S.A, Breinlinger, E.C. 登録日 2023-06-28 公開日 2023-10-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712. J.Med.Chem., 66, 2023
8TB6	TYK2 JH2 bound to Compound14 分子名称: N-[(3M)-3-{6-[(3R)-3-methoxyoxolan-3-yl]pyridin-2-yl}-1-methyl-1H-pyrrolo[2,3-c]pyridin-5-yl]urea, Non-receptor tyrosine-protein kinase TYK2 著者 Argiriadi, M.A, Van Epps, S.A, Breinlinger, E.C. 登録日 2023-06-28 公開日 2023-10-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712. J.Med.Chem., 66, 2023
4JQD	Crystal structure of the Restriction-Modification Controller Protein C.Csp231I OL operator complex 分子名称: Csp231I C protein, DNA (5'-D(*AP*CP*AP*CP*TP*AP*AP*GP*GP*AP*AP*AP*AP*CP*TP*TP*AP*GP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*AP*AP*GP*TP*TP*TP*TP*CP*CP*TP*TP*AP*GP*TP*GP*T)-3') 著者 Shevtsov, M.B, Streeter, S.D, Thresh, S.J, McGeehan, J.E, Kneale, G.G. 登録日 2013-03-20 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural analysis of DNA binding by C.Csp231I, a member of a novel class of R-M controller proteins regulating gene expression. Acta Crystallogr.,Sect.D, 71, 2015
4OT9	crystal structure of the C-terminal domain of p100/NF-kB2 分子名称: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION 著者 Tao, Z.H, Huang, D.B, Fusco, A, Gupta, K, Ware, C.F, Duynne, G.V. 登録日 2014-02-13 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation. Proc.Natl.Acad.Sci.USA, 111, 2014
1L9B	X-Ray Structure of the Cytochrome-c(2)-Photosynthetic Reaction Center Electron Transfer Complex from Rhodobacter sphaeroides in Type II Co-Crystals 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CHLORIDE ION, ... 著者 Axelrod, H.L, Abresch, E.C, Okamura, M.Y, Yeh, A.P, Rees, D.C, Feher, G. 登録日 2002-03-22 公開日 2002-06-12 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray structure determination of the cytochrome c2: reaction center electron transfer complex from Rhodobacter sphaeroides. J.Mol.Biol., 319, 2002
1L2G	Structure of a C-terminally truncated form of glycoprotein D from HSV-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein D 著者 Carfi, A, Willis, S.H, Whitbeck, J.C, Krummenacher, C, Cohen, G.H, Eisenberg, R.J, Wiley, D.C. 登録日 2002-02-21 公開日 2003-12-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol.Cell, 8, 2001
7Z2I	TRYPSIN (BOVINE) COMPLEXED WITH compound 4 分子名称: 5-[[3-(trifluoromethyl)phenyl]methyl]-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Schiering, N, Dalvit, C, Vulpetti, A. 登録日 2022-02-27 公開日 2022-05-25 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19 F NMR Binding Assay with Predicted 19 F NMR Chemical Shifts. Chemmedchem, 17, 2022
5OUJ	Crystal structure of human AKR1B1 complexed with NADP+ and compound 39 分子名称: 2-[(1~{R})-5-(4-chlorophenyl)-9-fluoranyl-3-methyl-1-oxidanyl-1~{H}-pyrimido[4,5-c]quinolin-2-yl]ethanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Metwally, K, Podjarny, A. 登録日 2017-08-24 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. Eur J Med Chem, 152, 2018
6KU8	structure of HRV-C 3C protein with rupintrivir 分子名称: 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, Genome polyprotein 著者 Zhu, L, Yuan, S. 登録日 2019-08-31 公開日 2020-03-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the HRV-C 3C-Rupintrivir Complex Provides New Insights for Inhibitor Design. Virol Sin, 35, 2020
5DFR	CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING 分子名称: CHLORIDE ION, DIHYDROFOLATE REDUCTASE 著者 Bystroff, C, Kraut, J. 登録日 1988-10-21 公開日 1990-07-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry, 30, 1991
2WY6	Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I 分子名称: CADMIUM ION, CALCIUM ION, GLYCEROL, ... 著者 Vachieri, S.G, Naylor, C.E, Basak, A.K. 登録日 2009-11-12 公開日 2009-11-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain Acta Crystallogr.,Sect.D, 66, 2011

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