6KU8

structure of HRV-C 3C protein with rupintrivir

Summary for 6KU8

• Entry DOI: 10.2210/pdb6ku8/pdb
• Descriptor: Genome polyprotein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER (3 entities in total)
• Functional Keywords: hrv, 3c, protease, rupintrivir, hydrolase
• Biological source: Rhinovirus C
• Total number of polymer chains: 1
• Total formula weight: 21209.13

Authors

Zhu, L.,Yuan, S. (deposition date: 2019-08-31, release date: 2020-03-25, Last modification date: 2023-11-22)

• Primary citation: Yuan, S.,Fan, K.,Chen, Z.,Sun, Y.,Hou, H.,Zhu, L.; Structure of the HRV-C 3C-Rupintrivir Complex Provides New Insights for Inhibitor Design.; Virol Sin, 35:445-454, 2020; PubMed: 32103448; DOI: 10.1007/s12250-020-00196-4

Experimental method

X-RAY DIFFRACTION (2.05 Å)