PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

---

2EXC	Inhibitor complex of JNK3 分子名称: Mitogen-activated protein kinase 10, N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE 著者 Xue, Y. 登録日 2005-11-08 公開日 2006-11-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Inhibitor complex of JNK3 To be Published
2EJQ	Conserved hypothetical protein (TTHA0227) from Thermo thermophilus HB8 分子名称: Hypothetical protein TTHA0227, MAGNESIUM ION 著者 Rehse, P.H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-20 公開日 2007-09-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Conserved hypothetical protein (TTHA0227) from Thermo thermophilus HB8 To be Published
3VPN	Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant 分子名称: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 著者 Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. 登録日 2012-03-05 公開日 2013-03-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Essential role of E106 in the proton-coupled electron transfer in human to be published
3VEK	Both Zn Fingers of GATA1 Bound to Palindromic DNA Recognition Site, P1 Crystal Form 分子名称: DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), Erythroid transcription factor, ... 著者 Jacques, D.A, Ripin, N, Wilkinson-White, L.E, Guss, J.M, Matthews, J.M. 登録日 2012-01-09 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA. Protein Sci., 24, 2015
3V7O	Crystal structure of the C-terminal domain of Ebola virus VP30 (strain Reston-89) 分子名称: 1,2-ETHANEDIOL, Minor nucleoprotein VP30 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-21 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of the Reston ebolavirus VP30 C-terminal domain. Acta Crystallogr F Struct Biol Commun, 70, 2014
3VOE	Crystal Structure of wild type MarR (apo form) from E.coli 分子名称: Multiple antibiotic resistance protein marR 著者 Lou, H, Zhu, R, Hao, Z. 登録日 2012-01-21 公開日 2013-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 MarR structures To be Published
3VA6	Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron 分子名称: Two-component system sensor histidine kinase 著者 Zhang, Z, Liu, Q, Hendrickson, W.A. 登録日 2011-12-28 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont To be Published
3VD6	Both Zn Fingers of GATA1 Bound to Palindromic DNA Recognition Site, P21 Crystal Form 分子名称: ACETATE ION, DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), ... 著者 Jacques, D.A, Ripin, N, Wilkinson-White, L.E, Guss, J.M, Matthews, J.M. 登録日 2012-01-04 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA. Protein Sci., 24, 2015
3VUT	Crystal structures of non-phosphorylated MAP2K4 分子名称: Dual specificity mitogen-activated protein kinase kinase 4 著者 Matsumoto, T, Kinoshita, T, Kirii, Y, Tada, T, Yamano, A. 登録日 2012-07-05 公開日 2012-09-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal and solution structures disclose a putative transient state of mitogen-activated protein kinase kinase 4 Biochem.Biophys.Res.Commun., 425, 2012
3VAV	Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, 3-methyl-2-oxobutanoate hydroxymethyltransferase, CHLORIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3VDX	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains 分子名称: Designed 16nm tetrahedral protein cage containing Non-haem bromoperoxidase BPO-A2 and Matrix protein 1 著者 Lai, Y.-T, Cascio, D, Yeates, T.O. 登録日 2012-01-06 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Structure of a 16-nm cage designed by using protein oligomers. Science, 336, 2012
3VPO	Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant 分子名称: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 著者 Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. 登録日 2012-03-05 公開日 2013-03-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Essential role of E106 in the proton-coupled electron transfer in human to be published
7CML	The Crystal Structure of human JNK2 from Biortus. 分子名称: Mitogen-activated protein kinase 9 著者 Wang, F, Lin, D, Cheng, W, Miao, Q, Huang, Y, Shang, H. 登録日 2020-07-28 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Crystal Structure of human JNK2 from Biortus. To Be Published
6QG4	Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine inhibitor 1h 分子名称: 1-[(3~{R})-3-[4-azanyl-3-(4-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-10 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QFR	Structure of the mitogen activated kinase kinase 7 dfg-out conformation 分子名称: Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-10 公開日 2019-05-22 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QHO	Dual specificity mitogen-activated protein kinase kinase 7 in complex with pyrazolopyrimidine 1a 分子名称: 1-[(3~{R})-3-(4-azanylpyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-17 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QFL	Structure of the mitogen activated kinase kinase 7 active conformation 分子名称: Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-10 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QFT	Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidin 1b 分子名称: 1-[(3~{R})-3-(4-azanyl-3-iodanyl-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-10 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QG7	Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine 1k 分子名称: (R)-1-(3-(4-amino-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-10 公開日 2019-05-22 最終更新日 2019-06-26 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
6QHR	Structure of the mitogen activated kinase kinase 7 in complex with pyrazolopyrimidine 1m 分子名称: 1-[(3~{R})-3-[4-azanyl-3-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 著者 Wolle, P, Mueller, M.P, Rauh, D. 登録日 2019-01-17 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7). J.Med.Chem., 62, 2019
3DGQ	Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J. 登録日 2008-06-15 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48, 2009
6R7F	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
3HJO	Crystal Structure of Glutathione Transferase Pi Y108V Mutant in Complex with the Glutathione Conjugate of Ethacrynic Acid 分子名称: CALCIUM ION, CARBONATE ION, ETHACRYNIC ACID, ... 著者 Parker, L.J. 登録日 2009-05-22 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
3HJM	Crystal structure of human Glutathione Transferase Pi Y108V mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2009-05-22 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
8WMM	Structure of CbCas9-PcrIIC1 complex bound to 28-bp DNA substrate (20-nt complementary) 分子名称: MAGNESIUM ION, NTS, PcrIIC1, ... 著者 Zhang, S, Lin, S, Liu, J.J.G. 登録日 2023-10-04 公開日 2024-06-05 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature, 630, 2024

<138139140141142143144145146147148149150151152153>