PDB: 45817 件ウェブページステータス検索Chemie searchBIRD

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4B9L	Structure of the high fidelity DNA polymerase I with the oxidative formamidopyrimidine-dA DNA lesion in the pre-insertion site. 分子名称: 5'-D(*CP*AP*GP*FAX*AP*GP*AP*GP*TP*CP*AP*GP*GP*CP*TP)-3', 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*TP)-3', DNA POLYMERASE I, ... 著者 Gehrke, T.H, Lischke, U, Arnold, S, Schneider, S, Carell, T. 登録日 2012-09-05 公開日 2013-04-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Unexpected Non-Hoogsteen-Based Mutagenicity Mechanism of Fapy-DNA Lesions. Nat.Chem.Biol., 9, 2013
5VRY	Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 20 s 分子名称: CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3'), ... 著者 Reed, A.J, Suo, Z. 登録日 2017-05-11 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
4Q44	Polymerase-Damaged DNA Complex 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*TP*CP*TP*AP*(RDG)P*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... 著者 Nair, D.T, Kottur, J, Sharma, A. 登録日 2014-04-13 公開日 2015-05-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic Structure, 23, 2015
5VS2	Human DNA polymerase beta pre-catalytic 8-oxoG:dA extension complex with dTTP bound in Watson-Crick conformation 分子名称: CALCIUM ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*A)-3'), ... 著者 Reed, A.J, Suo, Z. 登録日 2017-05-11 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
5VRW	Human DNA polymerase beta pre-catalytic 8-oxoG:dC extension complex with dTTP bound in non-planar conformation 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), ... 著者 Reed, A.J, Suo, Z. 登録日 2017-05-11 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
5VS4	Human DNA polymerase beta 8-oxoG:dA extension with dTTP after 120 s 分子名称: ACETATE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*AP*T)-3'), ... 著者 Reed, A.J, Suo, Z. 登録日 2017-05-11 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
4B9T	Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion -dC basepair in the post-insertion site. 分子名称: 5'-D(*AP*CP*CP*TP*GP*AP*CP*TP*CP*TP)-3', 5'-D(*CP*AP*TP*FOXP*AP*GP*AP*GP*TP*CP*AP*GP*GP*TP*TP)-3', DNA POLYMERASE, ... 著者 Gehrke, T.H, Lischke, U, Arnold, S, Schneider, S, Carell, T. 登録日 2012-09-06 公開日 2013-04-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Unexpected Non-Hoogsteen-Based Mutagenicity Mechanism of Fapy-DNA Lesions. Nat.Chem.Biol., 9, 2013
1ADU	EARLY E2A DNA-BINDING PROTEIN 分子名称: ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, ZINC ION 著者 Tucker, P.A, Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C. 登録日 1995-05-11 公開日 1996-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein. J.Mol.Biol., 257, 1996
3N1I	Crystal Structure of a StWhy2-ERE32 complex 分子名称: DNA 32-mer ERE32, protein StWhy2 著者 Cappadocia, L, Brisson, N, Sygusch, J. 登録日 2010-05-15 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of DNA-Whirly Complexes and Their Role in Arabidopsis Organelle Genome Repair. Plant Cell, 22, 2010
3N1L	Crystal Structure of a StWhy2-rcERE32 complex 分子名称: DNA 32-mer rcERE32, protein StWhy2 著者 Cappadocia, L, Brisson, N, Sygusch, J. 登録日 2010-05-15 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures of DNA-Whirly Complexes and Their Role in Arabidopsis Organelle Genome Repair. Plant Cell, 22, 2010
4Q43	Polymerase-damaged DNA complex 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*T*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*(RDG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... 著者 Kottur, J, Sharma, A, Nair, D.T. 登録日 2014-04-13 公開日 2015-05-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic Structure, 23, 2015
3N1J	Crystal structure of a StWhy2-dT32 complex 分子名称: DNA 32-mer dT32, Protein StWhy2 著者 Cappadocia, L, Brisson, N, Sygusch, J. 登録日 2010-05-15 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structures of DNA-Whirly Complexes and Their Role in Arabidopsis Organelle Genome Repair. Plant Cell, 22, 2010
3N1K	Crystal Structure of a StWhy2-cERE32 complex 分子名称: DNA 32-mer cERE32, protein StWhy2 著者 Cappadocia, L, Brisson, N, Sygusch, J. 登録日 2010-05-15 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 Crystal Structures of DNA-Whirly Complexes and Their Role in Arabidopsis Organelle Genome Repair. Plant Cell, 22, 2010
1ADV	EARLY E2A DNA-BINDING PROTEIN 分子名称: ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, ZINC ION 著者 Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C, Tucker, P.A. 登録日 1995-05-12 公開日 1996-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein. J.Mol.Biol., 257, 1996
2R8I	Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DC)-3'), ... 著者 Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. 登録日 2007-09-10 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV Biochemistry, 47, 2008
2R8H	Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DC)-3'), ... 著者 Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. 登録日 2007-09-10 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV Biochemistry, 47, 2008
4CCH	Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with d5SICS as templating nucleotide 分子名称: 5'-D(*AP*AP*CP*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP* C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3', DNA POLYMERASE I, ... 著者 Betz, K, Malyshev, D.A, Lavergne, T, Welte, W, Diederichs, K, Romesberg, F.E, Marx, A. 登録日 2013-10-23 公開日 2013-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Insights Into DNA Replication without Hydrogen Bonds. J.Am.Chem.Soc., 135, 2013
4MFC	Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-27 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4MFF	Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-27 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
3KTQ	CRYSTAL STRUCTURE OF AN ACTIVE TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'), ... 著者 Li, Y, Waksman, G. 登録日 1998-07-28 公開日 1999-01-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J., 17, 1998
3SQ2	RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (AT rich sequence) 分子名称: 5'-D(*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*G)-3', CALCIUM ION, ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-04 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
3SUO	RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite 2AP (GC rich sequence) 分子名称: 5'-D(*CP*GP*CP*GP*CP*GP*GP*CP*GP*GP*CP*GP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*CP*GP*CP*CP*GP*CP*CP*GP*CP*GP*CP*GP*G)-3', CALCIUM ION, ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-11 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
3TFR	Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CF2)PP in the active site 分子名称: 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Chamberlain, B.T, Batra, V.K, Beard, W.A, Kadina, A.P, Shock, D.D, Kashemirov, B.A, McKenna, C.E, Goodman, M.F, Wilson, S.H. 登録日 2011-08-16 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem, 13, 2012
3SQ4	RB69 DNA Polymerase Ternary Complex with dTTP Opposite 2AP (GC rich sequence) 分子名称: 5'-D(*CP*GP*CP*GP*CP*GP*GP*CP*GP*GP*CP*GP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*CP*GP*CP*CP*GP*CP*CP*GP*CP*GP*CP*GP*G)-3', CALCIUM ION, ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-04 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011
3SUQ	RB69 DNA Polymerase (Y567A) Ternary Complex with dCTP Opposite 2AP (AT rich sequence) 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*(2DA))-3', 5'-D(P*CP*(2PR)P*TP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*G)-3', ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-07-11 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Biochemistry, 50, 2011

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