3TFR
Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CF2)PP in the active site
Summary for 3TFR
Entry DOI | 10.2210/pdb3tfr/pdb |
Related | 3TFS |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total) |
Functional Keywords | dna polymerase, stereoselectivity, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 48444.45 |
Authors | Chamberlain, B.T.,Batra, V.K.,Beard, W.A.,Kadina, A.P.,Shock, D.D.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Wilson, S.H. (deposition date: 2011-08-16, release date: 2012-03-21, Last modification date: 2023-09-13) |
Primary citation | Chamberlain, B.T.,Batra, V.K.,Beard, W.A.,Kadina, A.P.,Shock, D.D.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Wilson, S.H. Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem, 13:528-530, 2012 Cited by PubMed: 22315190DOI: 10.1002/cbic.201100738 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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