5VRW
Human DNA polymerase beta pre-catalytic 8-oxoG:dC extension complex with dTTP bound in non-planar conformation
Summary for 5VRW
Entry DOI | 10.2210/pdb5vrw/pdb |
Related | 5VRX 5VRY 5VRZ 5VS0 5VS1 5VS2 5VS3 5VS4 |
Descriptor | DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total) |
Functional Keywords | polymerase, 8-oxoguanine, ber, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 49511.69 |
Authors | Reed, A.J.,Suo, Z. (deposition date: 2017-05-11, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Reed, A.J.,Suo, Z. Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139:9684-9690, 2017 Cited by PubMed: 28682600DOI: 10.1021/jacs.7b05048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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