5VRW
Human DNA polymerase beta pre-catalytic 8-oxoG:dC extension complex with dTTP bound in non-planar conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | T | DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3') | polymer | 16 | 4909.2 | 1 | synthetic construct | ||
2 | P | DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3') | polymer | 10 | 3021.0 | 1 | synthetic construct | ||
3 | D | DNA (5'-D(P*GP*TP*CP*GP*G)-3') | polymer | 5 | 1536.0 | 1 | synthetic construct | ||
4 | A | DNA polymerase beta | polymer | 341 | 39070.5 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB | Homo sapiens (Human) | |
5 | P, D, A | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
6 | P | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
7 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
8 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P06746)
PDB | External Database | Details |
---|---|---|
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 48536.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 975.0 | |
All* | Total formula weight | 49511.7 |