4Q44

Polymerase-Damaged DNA Complex

Summary for 4Q44

• Entry DOI: 10.2210/pdb4q44/pdb
• Related: 4Q43 4Q45
• Descriptor: DNA polymerase IV, DNA (5'-D(*TP*CP*TP*AP*(RDG)P*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, ... (5 entities in total)
• Functional Keywords: polymerase, dna polymerase, dna, transferase-dna complex, transferase/dna
• Biological source: Escherichia coli; More
• Cellular location: Cytoplasm : Q47155
• Total number of polymer chains: 6
• Total formula weight: 99958.70

Authors

Nair, D.T.,Kottur, J.,Sharma, A. (deposition date: 2014-04-13, release date: 2015-05-06, Last modification date: 2023-11-08)

• Primary citation: Kottur, J.,Sharma, A.,Gore, K.R.,Narayanan, N.,Samanta, B.,Pradeepkumar, P.I.,Nair, D.T.; Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic; Structure, 23:56-67, 2015; PubMed: 25497730; DOI: 10.1016/j.str.2014.10.019

Experimental method

X-RAY DIFFRACTION (2.71 Å)