2R8I
Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase
Summary for 2R8I
| Entry DOI | 10.2210/pdb2r8i/pdb |
| Related | 2R8G 2R8H |
| Descriptor | DNA (5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DC)-3'), DNA (5'-D(*DTP*DCP*DAP*DTP*(P)P*DGP*DAP*DAP*DTP*DCP*DCP*DTP*DTP*DCP*DCP*DCP*DCP*DC)-3'), DNA polymerase IV, ... (6 entities in total) |
| Functional Keywords | exocyclic adducts, replication bypass, translesion, polymerase, frameshifting, replication, transferase-dna complex, transferase/dna |
| Biological source | Sulfolobus solfataricus |
| Cellular location | Cytoplasm (Probable): Q97W02 |
| Total number of polymer chains | 3 |
| Total formula weight | 50393.52 |
| Authors | Wang, Y.,Saleh, S.,Marnette, L.J.,Egli, M.,Stone, M.P. (deposition date: 2007-09-10, release date: 2008-07-22, Last modification date: 2024-02-21) |
| Primary citation | Wang, Y.,Musser, S.K.,Saleh, S.,Marnett, L.J.,Egli, M.,Stone, M.P. Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV Biochemistry, 47:7322-7334, 2008 Cited by PubMed: 18563918DOI: 10.1021/bi800152j PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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