3BZ4
 
 | | Crystal structure of Fab F22-4 in complex with a Shigella flexneri 2a O-Ag decasaccharide | | 分子名称: | Fab F22-4 heavy chain, Fab F22-4 light chain, PALLADIUM ION, ... | | 著者 | Saul, F.A, Vulliez-le-Normand, B, Bentley, G.A. | | 登録日 | 2008-01-17 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C5S
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3SDY
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5LSP
 | | 107_A07 Fab in complex with fragment of the Met receptor | | 分子名称: | 107_A07 Fab heavy chain, 107_A07 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | DiCara, D, Chirgadze, D.Y, Pope, A, Karatt-Vellatt, A, Winter, A, van den Heuvel, J, Gherardi, E, McCafferty, J. | | 登録日 | 2016-09-05 | | 公開日 | 2017-09-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.605 Å) | | 主引用文献 | Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain.
Sci Rep, 7, 2017
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3C6S
 | | Crystal structure of Fab F22-4 in complex with a Shigella flexneri 2a O-Ag pentadecasaccharide | | 分子名称: | Fab F22-4 heavy chain, Fab F22-4 light chain, PALLADIUM ION, ... | | 著者 | Saul, F.A, Vulliez-le-Normand, B, Bentley, G.A. | | 登録日 | 2008-02-05 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody
Proc.Natl.Acad.Sci.Usa, 105, 2008
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7MPG
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3CLF
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3CLE
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1EGJ
 | | DOMAIN 4 OF THE BETA COMMON CHAIN IN COMPLEX WITH AN ANTIBODY | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ANTIBODY (LIGHT CHAIN), ... | | 著者 | Rossjohn, J, McKinstry, W.J, Woodcock, J.M, McClure, B.J, Hercus, T.R, Parker, M.W, Lopez, A.F, Bagley, C.J. | | 登録日 | 2000-02-15 | | 公開日 | 2001-02-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.
Blood, 95, 2000
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5DD6
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1UCB
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1H8O
 | | Three-dimensional structure of anti-ampicillin single chain Fv fragment. | | 分子名称: | MUTANT AL2 6E7P9G, SULFATE ION | | 著者 | Burmester, J, Spinelli, S, Pugliese, L, Krebber, A, Honegger, A, Jung, S, Schimmele, B, Cambillau, C, Pluckthun, A. | | 登録日 | 2001-02-14 | | 公開日 | 2001-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Selection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries
J.Mol.Biol., 309, 2001
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3GM0
 | | Anti-methamphetamine single chain Fv in complex with MDMA | | 分子名称: | (2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine, anti-methamphetamine single chain Fv | | 著者 | Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I. | | 登録日 | 2009-03-12 | | 公開日 | 2009-10-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
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7UT3
 | | Crystal structure of complex of Fab, G10C with GalNAc-pNP | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-nitrophenyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside, Fab protein heavy chain, ... | | 著者 | Li, M, Wlodawer, A. | | 登録日 | 2022-04-26 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O -GalNAcylation in Numerous Human Tissues and Cell Lines.
J.Am.Chem.Soc., 144, 2022
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7CJ2
 | | Crystal structure of the Fab antibody complexed with human YKL-40 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 3-like 1 (Cartilage glycoprotein-39), isoform CRA_a, ... | | 著者 | Choi, S, Na, J.H, Lee, S.J, Woo, J.R, Kim, D.Y, Hong, J.T, Lee, W.K. | | 登録日 | 2020-07-09 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the Fab antibody complexed with human YKL-40
To Be Published
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8SOS
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1Q9W
 | | S45-18 Fab pentasaccharide bisphosphate complex | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. | | 登録日 | 2003-08-26 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
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7PS3
 | | Crystal structure of antibody Beta-32 Fab | | 分子名称: | Beta-32 heavy chain, Beta-32 light chain, CHLORIDE ION, ... | | 著者 | Zhou, D, Ren, J, Stuart, D.I. | | 登録日 | 2021-09-22 | | 公開日 | 2021-12-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
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5NHW
 | | CRYSTAL STRUCTURE OF THE BIMAGRUMAB Fab | | 分子名称: | GLYCEROL, anti-human ActRII Bimagrumab Fab heavy-chain, anti-human ActRII Bimagrumab Fab light-chain | | 著者 | Rondeau, J.-M. | | 登録日 | 2017-03-22 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8STI
 | | human STING with agonist XMT-1616 | | 分子名称: | 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide, Stimulator of interferon genes protein | | 著者 | Duvall, J.R, Bukhalid, R.A. | | 登録日 | 2023-05-10 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates.
J.Med.Chem., 66, 2023
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1AIF
 | | ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB FROM MOUSE | | 分子名称: | ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (HEAVY CHAIN), ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A) FAB (LIGHT CHAIN) | | 著者 | Ban, N, Escobar, C, Hasel, K, Day, J, Greenwood, A, McPherson, A. | | 登録日 | 1994-11-14 | | 公開日 | 1997-02-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of an anti-idiotypic Fab against feline peritonitis virus-neutralizing antibody and a comparison with the complexed Fab.
FASEB J., 9, 1995
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8STH
 | | human STING with diABZI agonist 15 | | 分子名称: | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein | | 著者 | Duvall, J.R, Bukhalid, R.A. | | 登録日 | 2023-05-10 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates.
J.Med.Chem., 66, 2023
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5OLM
 | | TRIM21 | | 分子名称: | E3 ubiquitin-protein ligase TRIM21, ZINC ION | | 著者 | James, L.C. | | 登録日 | 2017-07-28 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
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8AON
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3LEF
 | | Crystal structure of HIV epitope-scaffold 4E10_S0_1Z6NA_001 | | 分子名称: | 1,2-ETHANEDIOL, Uncharacterized protein 4E10_S0_1Z6NA_001 (T18) | | 著者 | Holmes, M.A. | | 登録日 | 2010-01-14 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
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