3BZ4

Crystal structure of Fab F22-4 in complex with a Shigella flexneri 2a O-Ag decasaccharide

Summary for 3BZ4

• Entry DOI: 10.2210/pdb3bz4/pdb
• Related: 3C5S 3C6S
• Descriptor: Fab F22-4 light chain, Fab F22-4 heavy chain, alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-[alpha-D-glucopyranose-(1-4)]alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-[alpha-D-glucopyranose-(1-4)]alpha-L-rhamnopyranose-(1-3)-2-aminoethyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: o-antigen, lps, shigella flexneri, antibody complex, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 8
• Total formula weight: 197886.30

Authors

Saul, F.A.,Vulliez-le-Normand, B.,Bentley, G.A. (deposition date: 2008-01-17, release date: 2008-07-01, Last modification date: 2023-11-01)

• Primary citation: Vulliez-Le Normand, B.,Saul, F.A.,Phalipon, A.,Belot, F.,Guerreiro, C.,Mulard, L.A.,Bentley, G.A.; Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody; Proc.Natl.Acad.Sci.Usa, 105:9976-9981, 2008; PubMed: 18621718; DOI: 10.1073/pnas.0801711105

Experimental method

X-RAY DIFFRACTION (1.8 Å)