3GM0

Anti-methamphetamine single chain Fv in complex with MDMA

Summary for 3GM0

• Entry DOI: 10.2210/pdb3gm0/pdb
• Related: 3GKZ
• Descriptor: anti-methamphetamine single chain Fv, (2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine (3 entities in total)
• Functional Keywords: anti-methamphetamine antibody, single chain fv, therapeutic antibody, immune system
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 1
• Total formula weight: 27982.55

Authors

Celikel, R.,Peterson, E.C.,Owens, M.,Varughese, K.I. (deposition date: 2009-03-12, release date: 2009-10-06, Last modification date: 2011-07-13)

• Primary citation: Celikel, R.,Peterson, E.C.,Owens, S.M.,Varughese, K.I.; Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.; Protein Sci., 18:2336-2345, 2009; PubMed: 19760665; DOI: 10.1002/pro.244

Experimental method

X-RAY DIFFRACTION (2.4 Å)