PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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4Y7R	Crystal structure of WDR5 in complex with MYC MbIIIb peptide 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MYC MbIIIb peptide, ... 著者 Sun, Q, Phan, J, Olejniczak, E.T, Thomas, L.R, Fesik, S.W, Tansey, W.P. 登録日 2015-02-16 公開日 2015-04-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC. Mol.Cell, 58, 2015
4U4Y	Crystal structure of Pactamycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
1MV3	NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC 分子名称: Myc box dependent interacting protein 1 著者 Pineda-Lucena, A, Arrowsmith, C.H. 登録日 2002-09-24 公開日 2003-09-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J.Mol.Biol., 351, 2005
1MUZ	NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC 分子名称: Myc box dependent interacting protein 1 著者 Pineda-Lucena, A, Arrowsmith, C.H. 登録日 2002-09-24 公開日 2003-09-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J.Mol.Biol., 351, 2005
2VFT	Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sorbitol 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE, ... 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
2VFR	Alditol Oxidase from Streptomyces coelicolor A3(2): Native Enzyme 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
2VFU	Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Mannitol 分子名称: D-MANNITOL, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
2VFS	Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Xylitol 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, XYLITOL OXIDASE, ... 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
2VFV	Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sulphite 分子名称: (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, CHLORIDE ION, XYLITOL OXIDASE 著者 Forneris, F, Mattevi, A. 登録日 2007-11-05 公開日 2008-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
8WX0	PNPase of M.tuberculosis with its RNA substrate 分子名称: Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase, RNA (24-mer) 著者 Wang, N, Sheng, Y.N. 登録日 2023-10-27 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation. Arch.Biochem.Biophys., 754, 2024
8TJG	Structure of Nei2 from Mycobacterium smegmatis in complex with Zn2+ 分子名称: DNA-(apurinic or apyrimidinic site) lyase, ZINC ION 著者 Warren, G, Shuman, S. 登録日 2023-07-21 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of Nei2 from Mycobacterium smegmatis in complex with Zn2+ To Be Published
8UFD	Multidrug efflux pump MtEfpA bound with inhibitor BRD8000.3 分子名称: (1S,3S)-N-[6-bromo-5-(pyrimidin-2-yl)pyridin-2-yl]-2,2-dimethyl-3-(2-methylpropyl)cyclopropane-1-carboxamide, Integral membrane efflux protein EFPA, PHOSPHATIDYLETHANOLAMINE 著者 Wang, S, Liao, M. 登録日 2023-10-04 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition. Nat Commun, 15, 2024
8T41	Crystal structure of aminopeptidase N from Mycobacterium tuberculosis 分子名称: Aminopeptidase N, MAGNESIUM ION, ZINC ION 著者 Park, H.W, Moss, D.L, Landry, S.J. 登録日 2023-06-08 公開日 2024-04-17 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of aminopeptidase N from Mycobacterium tuberculosis To Be Published
8TA0	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM881 分子名称: 3-[2-(3-{[(6M)-2,4-diamino-6-(3-methoxyphenyl)pyrimidin-5-yl]oxy}propoxy)phenyl]propanoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-26 公開日 2024-08-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM881 To be published
8TBR	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758 分子名称: 3-(2-{3-[(2,4-diamino-6-phenylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-29 公開日 2024-08-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758 To be published
8TA1	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907 分子名称: 3-(2-{3-[(2,4-diamino-6-cyclohexylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ACETATE ION, Dihydrofolate reductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-26 公開日 2024-08-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907 To be published
8U12	Crystal Structure of Antitoxin Protein Rv0298 of Type II Toxin-antitoxin Systems from Mycobacterium tuberculosis 分子名称: Antitoxin Rv0298, SULFATE ION 著者 Kim, Y, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) 登録日 2023-08-30 公開日 2023-09-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Antitoxin Protein Rv0298 of Type II Toxin-antitoxin Systems from Mycobacterium tuberculosis To Be Published
8TXA	Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum 分子名称: tRNA (guanine-N(1)-)-methyltransferase 著者 Balsamo, A, Bruno, C, Edele, C, Fabian, T, Jannotta, R, Lee, R, Schryver, D, Warsaw, J, Warsaw, L, Stojanoff, V, Battaile, K, Perez, A, Bolen, R. 登録日 2023-08-23 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.591 Å) 主引用文献 Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum To Be Published
8U3P	1.79 Angstrom resolution crystal structure of KatG from Mycobacterium tuberculosis with an MYW cofactor after heat incubation for 60 minutes 分子名称: ACETATE ION, Catalase-peroxidase, GLYCEROL, ... 著者 Liu, A, Li, J, Ran, D. 登録日 2023-09-08 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 1.79 Angstrom resolution crystal structure of KatG from Mycobacterium tuberculosis with an MYW cofactor after heat incubation for 60 minutes To Be Published
7A10	LppS with covalent adduct derived from 1g 分子名称: 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A1E	LppS with covalent adduct derived from 1c 分子名称: ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-12 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A11	LppS with covalent adduct derived from 1E 分子名称: ACETATE ION, L,D-transpeptidase 2, propane-1-thiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A0Z	LppS with covalent adduct derived from 1b 分子名称: L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A1C	LdtMT2 with covalent adduct derived from N-Thio-beta-lactam 1a 分子名称: DIMETHYL SULFOXIDE, L,D-transpeptidase 2 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-12 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
8U2Q	Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) To be published

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