8WX0

PNPase of M.tuberculosis with its RNA substrate

Summary for 8WX0

Entry DOI	10.2210/pdb8wx0/pdb
EMDB information	37896
Descriptor	Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase, RNA (24-mer) (3 entities in total)
Functional Keywords	pnpase, mycobacterium tuberculosis, complex, transferase, transferase-rna complex, transferase/rna
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	7
Total formula weight	277080.19
Authors	Wang, N.,Sheng, Y.N. (deposition date: 2023-10-27, release date: 2024-07-03)
Primary citation	Wang, N.,Sheng, Y.,Liu, Y.,Guo, Y.,He, J.,Liu, J. Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation. Arch.Biochem.Biophys., 754:109917-109917, 2024 Cited by PubMed: 38395123 DOI: 10.1016/j.abb.2024.109917 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation