8TA1

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907

Summary for 8TA1

• Entry DOI: 10.2210/pdb8ta1/pdb
• Descriptor: Dihydrofolate reductase, SODIUM ION, ACETATE ION, ... (7 entities in total)
• Functional Keywords: ssgcid, structural genomics, seattle structural genomics center for infectious disease, dihydrofolate reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Mycobacterium ulcerans
• Total number of polymer chains: 1
• Total formula weight: 20664.01

Authors

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2023-06-26, release date: 2024-08-28)

• Primary citation: Woodward, E.L.,Lovell, S.,Mian, M.R.,Seibold, S.; Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907; To be published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)