7A1E
LppS with covalent adduct derived from 1c
Summary for 7A1E
| Entry DOI | 10.2210/pdb7a1e/pdb |
| Related | 7A0Z 7A10 7A11 7A1C |
| Descriptor | L,D-transpeptidase 2, phenylmethanethiol, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | transpeptidase, cell wall, peptidoglycan, antibiotic, beta-lactam, covalent inhibitor, mycobacterium tuberculosis, ligase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 2 |
| Total formula weight | 56798.96 |
| Authors | Schnell, R.,Steiner, E.M. (deposition date: 2020-08-12, release date: 2021-04-21, Last modification date: 2024-01-31) |
| Primary citation | Martelli, G.,Pessatti, T.B.,Steiner, E.M.,Cirillo, M.,Caso, C.,Bisognin, F.,Landreh, M.,Monte, P.D.,Giacomini, D.,Schnell, R. N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28:1321-, 2021 Cited by PubMed: 33826941DOI: 10.1016/j.chembiol.2021.03.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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