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6I3I
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Crystal structure of reactive center loop (RCL) cleaved angiotensinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen
著者Yan, Y, Read, R.J.
登録日2018-11-06
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
6F4M
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BU of 6f4m by Molmil
Human JMJD5 in its apo form.
分子名称: JmjC domain-containing protein 5
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-29
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
6F4T
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BU of 6f4t by Molmil
Human JMJD5 (W414C) in complex with Mn(II), NOG and RCCD1 (139-143) (complex-5)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, JmjC domain-containing protein 5, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-30
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
4LC2
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BU of 4lc2 by Molmil
Crystal structure of the bromodomain of human BRPF1B
分子名称: 1,2-ETHANEDIOL, NITRATE ION, Peregrin
著者Tallant, C, Nunez-Alonso, G, Savitsky, P, Picaud, S, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2013-06-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the bromodomain of human BRPF1B
TO BE PUBLISHED
5C0W
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BU of 5c0w by Molmil
Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates
分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
著者Makino, D.L, Conti, E.
登録日2015-06-12
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
4LE2
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BU of 4le2 by Molmil
Crystal structure of the unphosphorylated receiver domain of DesR in the active state
分子名称: PHOSPHATE ION, POTASSIUM ION, Transcriptional regulatory protein DesR
著者Trajtenberg, F, Larrieux, N, Buschiazzo, A.
登録日2013-06-25
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
6F4N
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BU of 6f4n by Molmil
Human JMJD5 in complex with MN and 2OG.
分子名称: 2-OXOGLUTARIC ACID, JmjC domain-containing protein 5, MANGANESE (II) ION
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-29
公開日2018-04-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.541 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
6INE
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BU of 6ine by Molmil
Crystal Structure of human ASH1L-MRG15 complex
分子名称: GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ...
著者Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M.
登録日2018-10-25
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 27, 2019
6F4S
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BU of 6f4s by Molmil
Human JMJD5 (N308C) in complex with Mn(II), 2OG and RCCD1 (139-143) (complex-4)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-OXOGLUTARIC ACID, GLYCEROL, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-30
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.461 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
7C9Q
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BU of 7c9q by Molmil
Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP
分子名称: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Huang, Y, Li, R, Wan, J.
登録日2020-06-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP
To Be Published
4ND5
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BU of 4nd5 by Molmil
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum
分子名称: Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase
著者Chattopadhyay, D, Cook, W.J.
登録日2013-10-25
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase.
Int.J.Biol.Macromol., 74C, 2014
1XIU
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BU of 1xiu by Molmil
Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR
分子名称: (9cis)-retinoic acid, Nuclear receptor coactivator 1, RXR-like protein
著者De Groot, A, De Rosny, E, Juillan-Binard, C, Ferrer, J.-L, Laudet, V, Pebay-Peroula, E, Fontecilla-Camps, J.-C, Borel, F.
登録日2004-09-22
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a Novel Tetrameric Complex of Agonist-bound Ligand-binding Domain of Biomphalaria glabrata Retinoid X Receptor.
J.Mol.Biol., 354, 2005
8AFK
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BU of 8afk by Molmil
Structure of iRFP variant C15S/N136R/V256C in complex with phycocyanobilin
分子名称: Near-infrared fluorescent protein, PHYCOCYANOBILIN
著者Remeeva, A, Kovalev, K, Gushchin, I, Fonin, A, Turoverov, K, Stepanenko, O.
登録日2022-07-18
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.015 Å)
主引用文献Structure of iRFP variant C15S/N136R/V256C in complex with phycocyanobilin
To Be Published
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
分子名称: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2017-11-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6F08
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BU of 6f08 by Molmil
14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1)
分子名称: 14-3-3 protein zeta/delta, PENTAETHYLENE GLYCOL, Son of sevenless homolog 1
著者Ballone, A, Centorrino, F, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-02-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of 14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1).
J. Struct. Biol., 202, 2018
6I3F
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BU of 6i3f by Molmil
Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, ...
著者Yan, Y, Read, R.J.
登録日2018-11-06
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
6F4R
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BU of 6f4r by Molmil
Human JMJD5 (N308C) in complex with Mn(II), NOG and RCCD1 (139-143) (complex-3)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, JmjC domain-containing protein 5, MANGANESE (II) ION, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-30
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
8ANV
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BU of 8anv by Molmil
Crystal structure of phi3T_93 and phi3T AimX complex
分子名称: Arbitrium putative lysogeny regulator, CALCIUM ION, NICKEL (II) ION, ...
著者Zamora-Caballero, S, Marina, A.
登録日2022-08-05
公開日2023-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Antagonistic interactions between phage and host factors control arbitrium lysis-lysogeny decision.
Nat Microbiol, 9, 2024
6LNI
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BU of 6lni by Molmil
Cryo-EM structure of amyloid fibril formed by full-length human prion protein
分子名称: Major prion protein
著者Wang, L.Q, Zhao, K, Yuan, H.Y, Wang, Q, Guan, Z.Y, Tao, J, Li, X.N, Hao, M.M, Chen, J, Zhang, D.L, Zhu, H.L, Yin, P, Liu, C, Liang, Y.
登録日2019-12-30
公開日2020-06-10
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.702 Å)
主引用文献Cryo-EM structure of an amyloid fibril formed by full-length human prion protein.
Nat.Struct.Mol.Biol., 27, 2020
1Z5X
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BU of 1z5x by Molmil
hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A
分子名称: 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, Ecdysone receptor ligand binding domain, PHOSPHATE ION, ...
著者Carmichael, J.A, Lawrence, M.C, Graham, L.D, Pilling, P.A, Epa, V.C, Noyce, L, Lovrecz, G, Winkler, D.A, Pawlak-Skrzecz, A.
登録日2005-03-21
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.
J.Biol.Chem., 280, 2005
7D0F
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BU of 7d0f by Molmil
cryo-EM structure of a pre-catalytic group II intron RNP
分子名称: Group II intron-encoded protein LtrA, RNA (738-MER)
著者Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
登録日2020-09-10
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
6LW2
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BU of 6lw2 by Molmil
The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase
分子名称: 7-chloranyl-4-[(3-methoxyphenyl)amino]-N-(4-methoxyphenyl)sulfonyl-1-methyl-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1
著者Wang, X.Y, Zhou, J, Xu, B.L.
登録日2020-02-07
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of N -Arylsulfonyl-Indole-2-Carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors-Design, Synthesis, In Vivo Glucose Lowering Effects, and X-ray Crystal Complex Analysis.
J.Med.Chem., 63, 2020
8BOR
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BU of 8bor by Molmil
Photosensory module from DrBphP without PHY tongue
分子名称: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome
著者Kurttila, M, Takala, H, Ihalainen, J.A.
登録日2022-11-15
公開日2023-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The interconnecting hairpin extension "arm": An essential allosteric element of phytochrome activity.
Structure, 31, 2023
6F4O
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BU of 6f4o by Molmil
Human JMJD5 in complex with Mn(II) and Succinate.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, JmjC domain-containing protein 5, MANGANESE (II) ION, ...
著者Chowdhury, R, Islam, M.S, Schofield, C.J.
登録日2017-11-29
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献JMJD5 is a human arginyl C-3 hydroxylase.
Nat Commun, 9, 2018
7D0G
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BU of 7d0g by Molmil
Cryo-EM structure of a pre-catalytic group II intron
分子名称: Group II intron-encoded protein LtrA, RNA (714-MER)
著者Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
登録日2020-09-10
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020

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