5C0W

Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates

Summary for 5C0W

Entry DOI	10.2210/pdb5c0w/pdb
Descriptor	Exosome complex component RRP45, Exosome complex exonuclease DIS3, Exosome complex exonuclease RRP6, ... (15 entities in total)
Functional Keywords	hydrolase, rna, nuclease, hydrolase-rna complex, hydrolase/rna
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	14
Total formula weight	514705.46
Authors	Makino, D.L.,Conti, E. (deposition date: 2015-06-12, release date: 2015-07-29, Last modification date: 2024-01-10)
Primary citation	Makino, D.L.,Schuch, B.,Stegmann, E.,Baumgartner, M.,Basquin, C.,Conti, E. RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524:54-58, 2015 Cited by PubMed: 26222026 DOI: 10.1038/nature14865 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.6 Å)

Structure validation