6F4R

Human JMJD5 (N308C) in complex with Mn(II), NOG and RCCD1 (139-143) (complex-3)

Summary for 6F4R

• Entry DOI: 10.2210/pdb6f4r/pdb
• Related: 6F4M 6F4N 6F4O 6F4P 6F4Q 6F4S 6F4T
• Descriptor: JmjC domain-containing protein 5, RCC1 domain-containing protein 1, MANGANESE (II) ION, ... (6 entities in total)
• Functional Keywords: oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, jmjc, jmjc domain, lysine-specific demethylase 8, jmjc domain-containing protein 5, arginyl c-3 hydroxylase, jmjd5, kdm8, oxygenase, hypoxia, dna-binding, metal-binding, translation, dsbh, facial triad, cytoplasm, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, beta-hydroxylation, hydroxylation, arginine hydroxylation, rcc1 domain-containing protein 1, rccd1, regulator of chromosome condensation, 40s ribosomal protein s6, rps6, ribosome biogenesis, transcription, epigenetic regulation, signaling, development, cell structure, transcription activator/inhibitor, phosphorylation, cancer, polymorphism
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30386.98

Authors

Chowdhury, R.,Islam, M.S.,Schofield, C.J. (deposition date: 2017-11-30, release date: 2018-04-04, Last modification date: 2024-01-17)

• Primary citation: Wilkins, S.E.,Islam, S.,Gannon, J.M.,Markolovic, S.,Hopkinson, R.J.,Ge, W.,Schofield, C.J.,Chowdhury, R.; JMJD5 is a human arginyl C-3 hydroxylase.; Nat Commun, 9:1180-1180, 2018; PubMed: 29563586; DOI: 10.1038/s41467-018-03410-w

Experimental method

X-RAY DIFFRACTION (1.3 Å)