PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

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4TZV	Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization 分子名称: Ribosome-associated protein L7Ae-like, T-box stem I, engineered tRNA 著者 Zhang, J, Ferre-D'Amare, A.R. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (5.03 Å) 主引用文献 Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
8OWV	H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F2, GLYCEROL, ... 著者 Mikolajek, H, Naismith, J.H, Owens, R.J. 登録日 2023-04-28 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2. Open Biology, 14, 2024
8F6Q	CryoEM structure of designed modular protein oligomer C8-71 分子名称: C8-71 著者 Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. 登録日 2022-11-17 公開日 2023-11-29 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. Biorxiv, 2023
8F6G	Crystal structure of BPTF bromodomain in complex with BZ2 分子名称: 6-[4-(2-aminoethyl)anilino]-5-chloro-3-methylpyrimidin-4(3H)-one, Nucleosome-remodeling factor subunit BPTF 著者 Nithianantham, S, Fischer, M. 登録日 2022-11-16 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of BPTF bromodomain in complex with BZ2 To Be Published
8PE2	Crystal structure of Gel4 in complex with Nanobody 3 分子名称: 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ... 著者 Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. 登録日 2023-06-13 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b-1,3-glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 2024
8OYT	Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ... 著者 Weckener, M, Naismith, J.H, Owens, R.J. 登録日 2023-05-05 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2. Open Biology, 14, 2024
8PE1	Crystal structure of Gel4 in complex with Nanobody 4 分子名称: 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ... 著者 Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. 登録日 2023-06-13 公開日 2024-06-19 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b-1,3-glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 2024
4U86	Human Pin1 with cysteine sulfonic acid 113 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Li, W, Zhang, Y. 登録日 2014-08-01 公開日 2015-04-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
4U2Z	X-ray crystal structure of an Sco GlgEI-V279S/1,2,2-trifluromaltose complex 分子名称: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, alpha-D-glucopyranose-(1-4)-2-deoxy-2,2-difluoro-alpha-D-arabino-hexopyranosyl fluoride 著者 Ronning, D.R, Lindenberger, J.J. 登録日 2014-07-18 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Synthesis of 2-deoxy-2,2-difluoro-alpha-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S. Org.Biomol.Chem., 13, 2015
4TZY	Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+ 分子名称: ADENINE, MAGNESIUM ION, STRONTIUM ION, ... 著者 Zhang, J, Ferre-D'Amare, A.R. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
8Q5W	MgADP-bound Fe protein of the molybdenum nitrogenase from Methanocaldococcus infernus 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Maslac, N, Wagner, T. 登録日 2023-08-09 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
4U85	Human Pin1 with cysteine sulfinic acid 113 分子名称: POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Li, W, Zhang, Y. 登録日 2014-08-01 公開日 2015-04-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
4U84	Human Pin1 with S-hydroxyl-cysteine 113 分子名称: POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Li, W, Zhang, Y. 登録日 2014-08-01 公開日 2015-04-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
3LJ6	3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH THE DRUG-LIKE UREA INHIBITOR PF-3845 at 2.42A RESOLUTION 分子名称: 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid, CHLORIDE ION, Fatty-acid amide hydrolase 1 著者 Mileni, M, Stevens, R.C, Kamtekar, S. 登録日 2010-01-25 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation J.Mol.Biol., 400, 2010
3KGS	V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5 分子名称: Transthyretin 著者 Trivella, D.B, Polikarpov, I. 登録日 2009-10-29 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J.Struct.Biol., 170, 2010
3KLM	17beta-HSD1 in complex with DHT 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL 著者 Mazumdar, M. 登録日 2009-11-08 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Mol.Endocrinol., 24, 2010
3KT2	Crystal Structure of N88D mutant HIV-1 Protease 分子名称: Protease 著者 Bihani, S.C, Das, A, Prashar, V, Ferrer, J.L, Hosur, M.V. 登録日 2009-11-24 公開日 2010-02-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S. Biochem.Biophys.Res.Commun., 389, 2009
3KT5	Crystal Structure of N88S mutant HIV-1 Protease 分子名称: Protease 著者 Bihani, S.C, Das, A, Prashar, V, Ferrer, J.L, Hosur, M.V. 登録日 2009-11-24 公開日 2010-02-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S. Biochem.Biophys.Res.Commun., 389, 2009
3LJ7	3D-crystal structure of humanized-rat fatty acid amide hydrolase (FAAH) conjugated with Carbamate inhibitor URB597 分子名称: CHLORIDE ION, CYCLOHEXANE AMINOCARBOXYLIC ACID, Fatty-acid amide hydrolase 1 著者 Mileni, M, Stevens, R.C, Kamtekar, S. 登録日 2010-01-25 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation J.Mol.Biol., 400, 2010
3LOW	Crystal structure of Beta 2 Microglobulin domain-swapped dimer 分子名称: Beta-2-microglobulin, GLYCEROL 著者 Liu, C, Eisenberg, D. 登録日 2010-02-04 公開日 2010-12-08 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat.Struct.Mol.Biol., 18, 2011
3LOZ	Crystal structure of Beta 2 Microglobulin amyloidogenic segment LSFSKD 分子名称: Beta-2-microglobulin segment LSFSKD 著者 Liu, C, Sawaya, M, Eisenberg, D. 登録日 2010-02-04 公開日 2010-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat.Struct.Mol.Biol., 18, 2011
2RCU	Crystal structure of rat carnitine palmitoyltransferase 2 in complex with r-3-(hexadecanoylamino)-4-(trimethylazaniumyl)butanoate 分子名称: (3R)-3-(hexadecanoylamino)-4-(trimethylammonio)butanoate, Carnitine O-palmitoyltransferase 2, octyl beta-D-glucopyranoside 著者 Rufer, A.C, Benz, J, Chomienne, O, Thoma, R, Hennig, M. 登録日 2007-09-20 公開日 2007-10-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Carnitine palmitoyltransferase 2: analysis of membrane association and complex structure with a substrate analog. Febs Lett., 581, 2007
4XII	X-ray structure of human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Knez, D, Boris, B, Coquelle, N, Sosic, I, Sink, R, Brazzolotto, X, Mravljak, J, Colletier, J.P, Gobec, S. 登録日 2015-01-07 公開日 2015-07-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents. Bioorg.Med.Chem., 23, 2015
2RGW	Catalytic Subunit of M. jannaschii Aspartate Transcarbamoylase 分子名称: Aspartate carbamoyltransferase, SULFATE ION 著者 Vitali, J, Colaneri, M.J, Kantrowitz, E.R. 登録日 2007-10-05 公開日 2008-10-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the catalytic trimer of Methanococcus jannaschii aspartate transcarbamoylase. Proteins, 71, 2008
2RKF	HIV-1 PR resistant mutant + LPV 分子名称: GLYCEROL, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, PROTEASE RETROPEPSIN, ... 著者 Rezacova, P, Brynda, J, Kozisek, M, Saskova, K.G, Konvalinka, J. 登録日 2007-10-16 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region J.Virol., 82, 2008

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