1OSS
 
 | | T190P STREPTOMYCES GRISEUS TRYPSIN IN COMPLEX WITH BENZAMIDINE | | 分子名称: | BENZAMIDINE, CALCIUM ION, SULFATE ION, ... | | 著者 | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | | 登録日 | 2003-03-20 | | 公開日 | 2003-08-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin.
Biochemistry, 42, 2003
|
|
1MBQ
 | | Anionic Trypsin from Pacific Chum Salmon | | 分子名称: | BENZAMIDINE, CALCIUM ION, Trypsin | | 著者 | Toyota, E, Ng, K.K.S, Kuninaga, S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G. | | 登録日 | 2002-08-03 | | 公開日 | 2002-12-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure and Nucleotide Sequence of an Anionic Trypsin from Chum Salmon (Oncorhynchus keta) in Comparison with Atlantic Salmon (Salmo salar) and Bovine Trypsin
J.Mol.Biol., 324, 2002
|
|
1D6R
 | | CRYSTAL STRUCTURE OF CANCER CHEMOPREVENTIVE BOWMAN-BIRK INHIBITOR IN TERNARY COMPLEX WITH BOVINE TRYPSIN AT 2.3 A RESOLUTION. STRUCTURAL BASIS OF JANUS-FACED SERINE PROTEASE INHIBITOR SPECIFICITY | | 分子名称: | BOWMAN-BIRK PROTEINASE INHIBITOR PRECURSOR, TRYPSINOGEN | | 著者 | Koepke, J, Ermler, U, Wenzl, G, Flecker, P. | | 登録日 | 1999-10-15 | | 公開日 | 2000-05-05 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
J.Mol.Biol., 298, 2000
|
|
1OS8
 | | RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN | | 分子名称: | CALCIUM ION, SULFATE ION, trypsin | | 著者 | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | | 登録日 | 2003-03-18 | | 公開日 | 2003-08-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin.
Biochemistry, 42, 2003
|
|
1ATE
 | |
2AYW
 | | Crystal Structure of the complex formed between trypsin and a designed synthetic highly potent inhibitor in the presence of benzamidine at 0.97 A resolution | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID, BENZAMIDINE, ... | | 著者 | Sherawat, M, Kaur, P, Perbandt, M, Betzel, C, Slusarchyk, W.A, Bisacchi, G.S, Chang, C, Jacobson, B.L, Einspahr, H.M, Singh, T.P. | | 登録日 | 2005-09-09 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
1CBW
 | | BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI | | 分子名称: | BOVINE CHYMOTRYPSIN, BPTI, SULFATE ION | | 著者 | Hynes, T.R, Scheidig, A.J, Kossiakoff, A.A. | | 登録日 | 1996-12-22 | | 公開日 | 1997-07-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
|
|
1CA0
 | | BOVINE CHYMOTRYPSIN COMPLEXED TO APPI | | 分子名称: | BOVINE CHYMOTRYPSIN, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR | | 著者 | Scheidig, A.J, Kossiakoff, A.A. | | 登録日 | 1997-01-23 | | 公開日 | 1997-07-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
|
|
2ZDK
 | | Exploring Trypsin S3 Pocket | | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Baum, B, Brandt, T, Heine, A, Klebe, G. | | 登録日 | 2007-11-26 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZDM
 | | Exploring trypsin S3 pocket | | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Baum, B, Brandt, T, Heine, A, Klebe, G. | | 登録日 | 2007-11-26 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZFT
 | | Exploring trypsin S3 pocket | | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Brandt, T, Baum, B, Heine, A, Klebe, G. | | 登録日 | 2008-01-11 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZDL
 | | Exploring trypsin S3 pocket | | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Baum, B, Brandt, T, Heine, A, Klebe, G. | | 登録日 | 2007-11-26 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZDN
 | | Exploring trypsin S3 pocket | | 分子名称: | (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Baum, B, Brandt, T, Heine, A, Klebe, G. | | 登録日 | 2007-11-26 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZFS
 | | Exploring trypsin S3 pocket | | 分子名称: | CALCIUM ION, Cationic trypsin, DIMETHYL SULFOXIDE, ... | | 著者 | Brandt, T, Baum, B, Heine, A, Klebe, G. | | 登録日 | 2008-01-10 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZHD
 | | Exploring trypsin S3 pocket | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Brandt, T, Baum, B, Heine, A, Klebe, G. | | 登録日 | 2008-02-04 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
|
|
2ZPR
 | |
2ZPS
 | |
2ZPQ
 | |
2GMT
 | | THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES | | 分子名称: | (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN | | 著者 | Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D. | | 登録日 | 1994-09-07 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Biochemistry, 33, 1994
|
|
1GCD
 | |
1W7Z
 | | Crystal structure of the free (uncomplexed) Ecballium elaterium trypsin inhibitor (EETI-II) | | 分子名称: | FORMIC ACID, SODIUM ION, TRYPSIN INHIBITOR II | | 著者 | Kraetzner, R, Debreczeni, J.E, Pape, T, Kolmar, H, Schneider, T.R, Uson, I, Scheldrick, G.M. | | 登録日 | 2004-09-14 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold
Acta Crystallogr.,Sect.D, 61, 2005
|
|
3RDY
 | |
1K2I
 | | Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin | | 分子名称: | 2,4-DIHYDROXY-TRANS CINNAMIC ACID, CHYMOTRYPSINOGEN A, SULFATE ION | | 著者 | Ghani, U, Ng, K.K.S, Atta-ur-Rahman, Choudhary, M.I, Ullah, N, James, M.N.G. | | 登録日 | 2001-09-27 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin.
J.Mol.Biol., 314, 2001
|
|
1TAB
 | | STRUCTURE OF THE TRYPSIN-BINDING DOMAIN OF BOWMAN-BIRK TYPE PROTEASE INHIBITOR AND ITS INTERACTION WITH TRYPSIN | | 分子名称: | BOWMAN-BIRK TYPE PROTEINASE INHIBITOR, TRYPSIN | | 著者 | Tsunogae, Y, Tanaka, I, Yamane, T, Kikkawa, J.-I, Ashida, T, Ishikawa, C, Watanabe, K, Nakamura, S, Takahashi, K. | | 登録日 | 1990-10-15 | | 公開日 | 1992-01-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the trypsin-binding domain of Bowman-Birk type protease inhibitor and its interaction with trypsin.
J.Biochem.(Tokyo), 100, 1986
|
|
1GGD
 | | CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-LEUCIL-PHENYLALANINE ALDEHYDE BOUND AT THE ACTIVE SITE | | 分子名称: | 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE, GAMMA CHYMOTRYPSIN, SULFATE ION | | 著者 | Neidhart, D, Wei, Y, Cassidy, C, Lin, J, Cleland, W.W, Frey, P.A. | | 登録日 | 2000-08-14 | | 公開日 | 2000-09-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2000
|
|
