2AYW
Crystal Structure of the complex formed between trypsin and a designed synthetic highly potent inhibitor in the presence of benzamidine at 0.97 A resolution
Summary for 2AYW
Entry DOI | 10.2210/pdb2ayw/pdb |
Descriptor | Cationic trypsin, CALCIUM ION, 2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID, ... (7 entities in total) |
Functional Keywords | trypsin, benzamidine, inhibitor, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 24839.00 |
Authors | Sherawat, M.,Kaur, P.,Perbandt, M.,Betzel, C.,Slusarchyk, W.A.,Bisacchi, G.S.,Chang, C.,Jacobson, B.L.,Einspahr, H.M.,Singh, T.P. (deposition date: 2005-09-09, release date: 2006-01-17, Last modification date: 2023-10-25) |
Primary citation | Sherawat, M.,Kaur, P.,Perbandt, M.,Betzel, C.,Slusarchyk, W.A.,Bisacchi, G.S.,Chang, C.,Jacobson, B.L.,Einspahr, H.M.,Singh, T.P. Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution. Acta Crystallogr.,Sect.D, 63:500-507, 2007 Cited by PubMed: 17372355DOI: 10.1107/S090744490700697X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.97 Å) |
Structure validation
Download full validation report