2ZFS
Exploring trypsin S3 pocket
Summary for 2ZFS
Entry DOI | 10.2210/pdb2zfs/pdb |
Related | 1K1P 2ZDK 2ZDL 2ZDM 2ZDN |
Related PRD ID | PRD_000588 |
Descriptor | Cationic trypsin, CALCIUM ION, N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide, ... (6 entities in total) |
Functional Keywords | hydrolase inhibitors, digestion, metal-binding, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (Bovine) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23934.12 |
Authors | Brandt, T.,Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-01-10, release date: 2009-01-13, Last modification date: 2023-11-01) |
Primary citation | Brandt, T.,Holzmann, N.,Muley, L.,Khayat, M.,Wegscheid-Gerlach, C.,Baum, B.,Heine, A.,Hangauer, D.,Klebe, G. Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties J.Mol.Biol., 405:1170-1187, 2011 Cited by PubMed: 21111747DOI: 10.1016/j.jmb.2010.11.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
Download full validation report