6WPT
 
 | | Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ... | | 著者 | Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2020-04-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
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3MJ9
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4XVJ
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4XZU
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6PYD
 | | Structure of 3E9 antibody Fab bound to marinobufagenin | | 分子名称: | (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, 3E9 anti-marinobufagenin antibody Fab heavy chain, recloned with human IgG4 C region, ... | | 著者 | Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J. | | 登録日 | 2019-07-29 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
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4RWY
 | | Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Acharya, P, Luongo, T.S, Kwong, P.D. | | 登録日 | 2014-12-08 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.128 Å) | | 主引用文献 | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
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1QFU
 | | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ... | | 著者 | Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M. | | 登録日 | 1999-04-14 | | 公開日 | 1999-04-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999
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6PYC
 | | Structure of kappa-on-heavy (KoH) antibody Fab bound to the cardiac hormone marinobufagenin | | 分子名称: | (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, KoH body Fab heavy chain, KoH body Fab light chain, ... | | 著者 | Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J. | | 登録日 | 2019-07-29 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
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4XMP
 | | Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120 | | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | | 登録日 | 2015-01-15 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7831 Å) | | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
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6WWC
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6WX2
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6F0D
 | | Crystal structure of a llama VHH antibody BCD090-M2 against human ErbB3 in space group P1 with cadmium ions | | 分子名称: | CADMIUM ION, VHH antibody BCD090-M2 | | 著者 | Eliseev, I.E, Yudenko, A.N, Vysochinskaya, V.V, Svirina, A.A, Evstratyeva, A.V, Drozhzhachih, M.S, Krendeleva, E.A, Vladimirova, A.K, Nemankin, T.A, Ekimova, V.M, Ulitin, A.B, Lomovskaya, M.I, Yakovlev, P.A, Moiseenko, F.V, Chakchir, O.B. | | 登録日 | 2017-11-19 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.90000749 Å) | | 主引用文献 | Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor.
F1000Res, 7, 2018
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4XNZ
 | | Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | | 登録日 | 2015-01-16 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.389 Å) | | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
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4XNY
 | | Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, ... | | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | | 登録日 | 2015-01-16 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
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1IT9
 | | CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A | | 分子名称: | HUMANIZED ANTIBODY HFE7A, HEAVY CHAIN, LIGHT CHAIN | | 著者 | Ito, S, Takayama, T, Hanzawa, H, Takahashi, T, Miyadai, K, Serizawa, N, Hata, T, Haruyama, H. | | 登録日 | 2002-01-11 | | 公開日 | 2003-02-25 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Humanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment
BIOL.PHARM.BULL., 25, 2002
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3QG7
 | | Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody | | 分子名称: | AP4-24H11 Antibody Heavy Chain, AP4-24H11 Antibody Light Chain, HEXAETHYLENE GLYCOL, ... | | 著者 | Kirchdoerfer, R.K, Kaufmann, G.F, Janda, J.D, Wilson, I.A. | | 登録日 | 2011-01-24 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
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1EMT
 | | FAB ANTIBODY FRAGMENT OF AN C60 ANTIFULLERENE ANTIBODY | | 分子名称: | IGG ANTIBODY (HEAVY CHAIN), IGG ANTIBODY (LIGHT CHAIN) | | 著者 | Braden, B.C, Goldbaum, F.A, Chen, B.-X, Erlanger, B.F, Kirschner, A.N, Wilson, S.R. | | 登録日 | 2000-03-17 | | 公開日 | 2000-11-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | X-ray crystal structure of an anti-Buckminsterfullerene antibody fab fragment: biomolecular recognition of C(60).
Proc.Natl.Acad.Sci.USA, 97, 2000
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6NN3
 | | Structure of parvovirus B19 decorated with Fab molecules from a human antibody | | 分子名称: | Fab monoclonal antibody 860-55D, heavy chain, light chain, ... | | 著者 | Rossmann, M.G, Sun, Y, Klose, T, Liu, Y. | | 登録日 | 2019-01-14 | | 公開日 | 2019-02-13 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
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1A4J
 | | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | | 分子名称: | IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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7L0N
 | | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity | | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Snell, G, Czudnochowski, N, Dillen, J, Nix, J.C, Croll, T.I, Corti, D. | | 登録日 | 2020-12-11 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.
Cell, 184, 2021
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4H20
 | | Crystal Structure and Computational Modeling of the Fab Fragment from the Protective anti-Ricin Monoclonal Antibody RAC18 | | 分子名称: | Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18 | | 著者 | Zhao, Z, Worthylake, D.K, LeCour Jr, L.F, Maresh, G, Pincus, S.H. | | 登録日 | 2012-09-11 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.
Plos One, 7, 2012
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1KN2
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | 分子名称: | IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL L-ALANINE, ... | | 著者 | Gigant, B, Knossow, M. | | 登録日 | 2001-12-18 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
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1KN4
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | 分子名称: | IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL D-ALANINE, ... | | 著者 | Gigant, B, Knossow, M. | | 登録日 | 2001-12-18 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
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8GKL
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7TB8
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | | 登録日 | 2021-12-21 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
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