PDB: 909 件ウェブページステータス検索Chemie searchBIRD

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6GSN	Structure of a partial yeast 48S preinitiation complex in closed conformation 分子名称: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Ramakrishnan, V. 登録日 2018-06-14 公開日 2019-06-26 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (5.75 Å) 主引用文献 Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
6NCQ	The dimerization domain of human SFPQ in space group C2221 分子名称: Splicing factor, proline- and glutamine-rich 著者 Lee, M. 登録日 2018-12-12 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ. Acta Crystallogr.,Sect.F, 75, 2019
6NSX	Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif 分子名称: CHLORIDE ION, HIV Tat-specific factor 1, Hsh155 著者 Jenkins, J.L, Leach, J.R, Kielkopf, C.L. 登録日 2019-01-25 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction. Rna, 25, 2019
6R5K	Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase 分子名称: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ... 著者 Schaefer, I.B, Conti, E. 登録日 2019-03-25 公開日 2019-05-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell, 177, 2019
5ZUH	Solution structure of RRM domain of La protein from Trypanosoma brucei 分子名称: RNA binding protein La-like protein 著者 Shan, F.Z. 登録日 2018-05-07 公開日 2019-05-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis. Febs J., 286, 2019
6DBP	RNA-recognition motif 1 of human MSI2 分子名称: RNA-binding protein Musashi homolog 2 著者 Goldgur, Y, Kharas, M.G, Minuesa, G. 登録日 2018-05-03 公開日 2019-05-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun, 10, 2019
6J6G	Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom 分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6H	Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom 分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6Q	Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6N	Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6QW6	Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-05 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6QX9	Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-07 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6HIP	Structure of SPF45 UHM bound to HIV-1 Rev ULM 分子名称: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... 著者 Pabis, M, Corsini, L, Sattler, M. 登録日 2018-08-30 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
6FF7	human Bact spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... 著者 Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. 登録日 2018-01-03 公開日 2019-03-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
6ICZ	Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6ID1	Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6QDV	Human post-catalytic P complex spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. 登録日 2019-01-03 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
6GBM	Solution structure of FUS-RRM bound to stem-loop RNA 分子名称: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS 著者 Loughlin, F.E, Allain, F.H.-T. 登録日 2018-04-15 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
6C8U	Solution structure of Musashi2 RRM1 分子名称: RNA-binding protein Musashi homolog 2 著者 Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L. 登録日 2018-01-25 公開日 2019-01-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins, 2019
6GC5	Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM 分子名称: AU-rich RNA, ELAV-like protein 1 著者 Ripin, N, Allain, F.H. 登録日 2018-04-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N3D	Structure of HIV Tat-specific factor 1 U2AF Homology Motif (APO-State) 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Loerch, S, Jenkins, J.L, Kielkopf, C.L. 登録日 2018-11-15 公開日 2019-01-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
6N3E	Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 分子名称: FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ... 著者 Loerch, S, Jenkins, J.L, Kielkopf, C.L. 登録日 2018-11-15 公開日 2019-01-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.893 Å) 主引用文献 The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
6N3F	Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, HIV Tat-specific factor 1, ... 著者 Leach, J.R, Jenkins, J.L, Kielkopf, C.L. 登録日 2018-11-15 公開日 2019-01-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
6E4N	Structure of the T. brucei TbRGG2 RRM domain: apo R3 crystal form 分子名称: RNA-binding protein, putative 著者 Schumacher, M.A. 登録日 2018-07-18 公開日 2018-12-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019

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