6DBP

RNA-recognition motif 1 of human MSI2

Summary for 6DBP

• Entry DOI: 10.2210/pdb6dbp/pdb
• Descriptor: RNA-binding protein Musashi homolog 2 (2 entities in total)
• Functional Keywords: musashi2 rna recognition motif, rna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 19186.08

Authors

Goldgur, Y.,Kharas, M.G.,Minuesa, G. (deposition date: 2018-05-03, release date: 2019-05-08, Last modification date: 2023-10-04)

• Primary citation: Minuesa, G.,Albanese, S.K.,Xie, W.,Kazansky, Y.,Worroll, D.,Chow, A.,Schurer, A.,Park, S.M.,Rotsides, C.Z.,Taggart, J.,Rizzi, A.,Naden, L.N.,Chou, T.,Gourkanti, S.,Cappel, D.,Passarelli, M.C.,Fairchild, L.,Adura, C.,Glickman, J.F.,Schulman, J.,Famulare, C.,Patel, M.,Eibl, J.K.,Ross, G.M.,Bhattacharya, S.,Tan, D.S.,Leslie, C.S.,Beuming, T.,Patel, D.J.,Goldgur, Y.,Chodera, J.D.,Kharas, M.G.; Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.; Nat Commun, 10:2691-2691, 2019; PubMed: 31217428; DOI: 10.1038/s41467-019-10523-3

Experimental method

X-RAY DIFFRACTION (1.603 Å)