PDB: 871 件ウェブページステータス検索Chemie searchBIRD

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6HCO	Cryo-EM structure of the ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... 著者 Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. 登録日 2018-08-15 公開日 2018-11-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature, 563, 2018
6HIJ	Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked 分子名称: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATP-binding cassette sub-family G member 2, CHOLESTEROL, ... 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. 登録日 2018-08-30 公開日 2018-09-19 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat.Struct.Mol.Biol., 25, 2018
6O2P	Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR) 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... 著者 Liu, F, Zhang, Z, Chen, J, Levit, A, Shoichet, B. 登録日 2019-02-24 公開日 2019-06-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
6O1V	Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B. 登録日 2019-02-21 公開日 2019-06-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
6O30	Lipid A transporter MsbA from Salmonella typhimurium 分子名称: Lipid A export ATP-binding/permease protein MsbA 著者 Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. 登録日 2019-02-25 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.47 Å) 主引用文献 Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
6OIH	Crystal structure of O-antigen polysaccharide ABC-transporter 分子名称: ABC transporter, LAURYL DIMETHYLAMINE-N-OXIDE, Transport permease protein 著者 Bi, Y, Zimmer, J. 登録日 2019-04-09 公開日 2019-04-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 Architecture of a channel-forming O-antigen polysaccharide ABC transporter. Nature, 553, 2018
6PAM	Structure of a bacterial Atm1-family ABC transporter with MgADP bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6P6J	Structure of YbtPQ importer with substrate Ybt-Fe bound 分子名称: ABC transporter protein, FE (III) ION, inner membrane ABC-transporter, ... 著者 Wang, Z, Hu, W, Zheng, H. 登録日 2019-06-04 公開日 2020-03-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Sci Adv, 6, 2020
6PAN	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PAQ	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6P6I	Structure of YbtPQ importer 分子名称: ABC transporter protein, inner membrane ABC-transporter 著者 Wang, Z, Hu, W, Zheng, H. 登録日 2019-06-04 公開日 2020-03-04 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Sci Adv, 6, 2020
6PAO	Structure of a bacterial Atm1-family ABC exporter with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATM1-type heavy metal exporter 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PAR	Structure of a bacterial Atm1-family ABC exporter with MgAMPPNP bound 分子名称: ATM1-type heavy metal exporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Fan, C, Kaiser, J.T, Rees, D.C. 登録日 2019-06-11 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
6PZB	Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state 分子名称: ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZI	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZA	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6Q81	Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state 分子名称: ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) 著者 Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. 登録日 2018-12-13 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
6PZ9	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZC	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine 分子名称: ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.34 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6QEX	Nanodisc reconstituted human ABCB1 in complex with UIC2 fab and taxol 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... 著者 Alam, A, Locher, K.P. 登録日 2019-01-08 公開日 2019-02-27 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insight into substrate and inhibitor discrimination by human P-glycoprotein. Science, 363, 2019
6QV2	Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2 分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ... 著者 Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. 登録日 2019-03-01 公開日 2019-05-29 最終更新日 2019-06-05 実験手法 X-RAY DIFFRACTION (4.23 Å) 主引用文献 The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
6QV1	Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1 分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ... 著者 Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. 登録日 2019-03-01 公開日 2019-05-29 最終更新日 2019-06-05 実験手法 X-RAY DIFFRACTION (3.48 Å) 主引用文献 The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
5W81	Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION 著者 Zhang, Z, Liu, F, Chen, J. 登録日 2017-06-21 公開日 2017-07-19 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Conformational Changes of CFTR upon Phosphorylation and ATP Binding. Cell, 170, 2017
5WUA	Structure of a Pancreatic ATP-sensitive Potassium Channel 分子名称: ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1 著者 Li, N, Wu, J.-X, Chen, L, Gao, N. 登録日 2016-12-16 公開日 2017-01-25 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Structure of a Pancreatic ATP-Sensitive Potassium Channel Cell, 168, 2017
5WS4	Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii 分子名称: 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, Macrolide export ATP-binding/permease protein MacB 著者 Murakami, S, Okada, U, Yamashita, E. 登録日 2016-12-05 公開日 2017-11-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii. Nat Commun, 8, 2017

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