PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4KRR	Crystal structure of Drosophila WntD N-terminal domain-linker (residues 31-240) 分子名称: GLYCEROL, SODIUM ION, Wnt inhibitor of Dorsal protein 著者 Chu, M.L.-H, Choi, H.-J, Ahn, V.E, Daniels, D.L, Nusse, R, Weis, W.I. 登録日 2013-05-16 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.124 Å) 主引用文献 Structural Studies of Wnts and Identification of an LRP6 Binding Site. Structure, 21, 2013
4OMP	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
3UVD	Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in complex with N-Methyl-2-pyrrolidone 分子名称: 1-methylpyrrolidin-2-one, Transcription activator BRG1 著者 Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
4ONE	Crystal Structure of a 3-oxoacyl-[acyl-carrier protein] reductase from Brucella melitensis 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-oxoacyl-(Acyl-carrier protein) reductase, CHLORIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-01-28 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of a 3-oxoacyl-[acyl-carrier protein] reductase from Brucella melitensis To be Published
3V2I	Structure of a Peptidyl-tRNA hydrolase (PTH) from Burkholderia thailandensis 分子名称: CITRIC ACID, Peptidyl-tRNA hydrolase, UNKNOWN LIGAND 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-12 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4DCQ	Crystal Structure of the Fab Fragment of 3B5H10, an Antibody-Specific for Extended Polyglutamine Repeats (orthorhombic form) 分子名称: 1,2-ETHANEDIOL, 3B5H10 FAB Heavy Chain, 3B5H10 FAB Light Chain 著者 Peters-Libeu, C.A, Tran, T, Finkbeiner, S, Weisgraber, K. 登録日 2012-01-18 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. J.Mol.Biol., 421, 2012
3UVR	Human p38 MAP Kinase in Complex with KM064 分子名称: 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{3-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D. 登録日 2011-11-30 公開日 2012-12-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献
3UW2	X-ray Crystal Structure of Phosphoglucomutase/phosphomannomutase family protein (BTH_I1489)from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-30 公開日 2012-02-01 最終更新日 2013-10-23 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4OBH	Crystal Structure of Inactive HIV-1 Protease in Complex with the p1-p6 substrate variant (L449F) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... 著者 Kolli, M. 登録日 2014-01-07 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 HIV-1 protease-substrate coevolution in nelfinavir resistance. J.Virol., 88, 2014
3UZU	The structure of the Ribosomal RNA small subunit methyltransferase A from Burkholderia pseudomallei 分子名称: 1,2-ETHANEDIOL, Ribosomal RNA small subunit methyltransferase A 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-07 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of the Ribosomal RNA small subunit methyltransferase A from Burkholderia pseudomallei TO BE PUBLISHED
3V0Q	Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP and H-antigen acceptor 分子名称: GLYCEROL, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Palcic, M.M, Jorgensen, R. 登録日 2011-12-08 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
4OCY	Fab for methotrexate (unbound apo) 分子名称: Fab ADD058 Heavy Chain, Fab ADD058 Light Chain 著者 Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. 登録日 2014-01-09 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
4OEX	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors 分子名称: 6-ethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Chen, T.T, Ren, J, Xu, Y.C. 登録日 2014-01-14 公開日 2015-04-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors. J.Med.Chem., 57, 2014
4OFX	Crystal Structure of a Putative Cystathionine beta-Synthase from Coxiella burnetii 分子名称: Cystathionine beta-synthase, SODIUM ION 著者 Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-01-15 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal Structure of a Putative Cystathionine beta-Synthase from Coxiella burnetii To be Published
4OJ4	Crystal structure of V290M PPARgamma mutant in complex with diclofenac 分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, CALCIUM ION, Peroxisome proliferator-activated receptor gamma 著者 Puhl, A.C, Webb, P, Polikarpov, I. 登録日 2014-01-20 公開日 2015-02-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a PPAR ligand-resistance syndrome mutant To be Published
3UZW	Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ 分子名称: 3-oxo-5-beta-steroid 4-dehydrogenase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Chen, M, Christianson, D.W, Penning, T.M. 登録日 2011-12-07 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.892 Å) 主引用文献 Conversion of Human Steroid 5beta-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING. J.Biol.Chem., 287, 2012
4OJF	Humanised 3D6 Fab complexed to amyloid beta 1-8 分子名称: Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain 著者 Miles, L.A, Crespi, G.A.N, Parker, M.W. 登録日 2014-01-21 公開日 2015-01-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta ACTA CRYSTALLOGR.,SECT.F, 70, 2014
3UNV	Pantoea agglomerans Phenylalanine Aminomutase 分子名称: (3S)-3-amino-3-phenylpropanoic acid, 1,2-ETHANEDIOL, AdmH, ... 著者 Geiger, J, Strom, S. 登録日 2011-11-16 公開日 2012-02-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Insights into the mechanistic pathway of the Pantoea agglomerans phenylalanine aminomutase. Angew.Chem.Int.Ed.Engl., 51, 2012
3V2L	Structure of Anopheles gambiae odorant binding protein 20 bound to polyethylene glycol 分子名称: AGAP005208-PA, TETRAETHYLENE GLYCOL 著者 Ziemba, B.P, Jones, D.N. 登録日 2011-12-12 公開日 2012-10-17 最終更新日 2012-12-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel mechanism of ligand binding and release in the odorant binding protein 20 from the malaria mosquito Anopheles gambiae. Protein Sci., 22, 2013
3V2O	Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 分子名称: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 著者 Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2011-12-12 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
3V31	Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 分子名称: Ankyrin repeat family A protein 2, CHLORIDE ION, Histone deacetylase 4, ... 著者 Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2011-12-12 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
4ONV	Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate 分子名称: 1,2-ETHANEDIOL, 2-KETO-3-DEOXYGLUCONATE, GLYCEROL, ... 著者 Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S. 登録日 2014-01-29 公開日 2015-01-14 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate To be Published
4O8K	Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis, apo structure 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-12-28 公開日 2014-01-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis, apo structure To be Published
4OP7	Crystal structure of P domain from norovirus strain NSW0514 in complex with HBGA type B (triglycan) 分子名称: IMIDAZOLE, VP1, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose 著者 Singh, B.K, Hansman, G.S. 登録日 2014-02-05 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Human noroviruses' fondness for histo-blood group antigens. J.Virol., 89, 2015
4OBC	Crystal structure of HCV polymerase NS5b genotype 2a JFH-1 isolate with the S15G, C223H, V321I resistance mutations against the guanosine analog GS-0938 (PSI-3529238) 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Edwards, T.E, Abendroth, J, Appleby, T.C. 登録日 2014-01-07 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance. Antimicrob.Agents Chemother., 58, 2014

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