PDB: 35439 件ウェブページステータス検索Chemie searchBIRD

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8PEO	H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex 分子名称: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ... 著者 Koutna, E, Kouba, T, Veverka, V. 登録日 2023-06-14 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
6Z9C	Structure of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability 分子名称: Polymerase delta-interacting protein 2, SODIUM ION 著者 Kulik, A.A, Maruszczak, K, Nabi, N.L.M, Bingham, R.J, Cooper, C.D.O. 登録日 2020-06-03 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability. Protein Sci., 30, 2021
4EYV	Crystal structure of Cyclophilin A like protein from Piriformospora indica 分子名称: PHOSPHATE ION, POTASSIUM ION, Peptidyl-prolyl cis-trans isomerase, ... 著者 Bhatt, H, Pal, R.K, Tuteja, N, Bhavesh, N.S. 登録日 2012-05-02 公開日 2013-05-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of RNA-interacting Cyclophilin A-like protein from Piriformospora indica that provides salinity-stress tolerance in plants Sci Rep, 3, 2013
1QR4	TWO FIBRONECTIN TYPE-III DOMAIN SEGMENT FROM CHICKEN TENASCIN 分子名称: PROTEIN (TENASCIN) 著者 Piontek, K, Bisig, D.A. 登録日 1999-06-17 公開日 1999-06-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Purification, crystallization and preliminary crystallographic studies of a two fibronectin type-III domain segment from chicken tenascin encompassing the heparin- and contactin-binding regions. Acta Crystallogr.,Sect.D, 55, 1999
1R8U	NMR structure of CBP TAZ1/CITED2 complex 分子名称: CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION 著者 De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. 登録日 2003-10-28 公開日 2004-03-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites. J.Biol.Chem., 279, 2004
8CBQ	structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Novacek, J, Veverka, V. 登録日 2023-01-25 公開日 2023-09-06 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
8CBN	structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Novacek, J, Veverka, V. 登録日 2023-01-25 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
3K3K	Crystal structure of dimeric abscisic acid (ABA) receptor pyrabactin resistance 1 (PYR1) with ABA-bound closed-lid and ABA-free open-lid subunits 分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYR1 著者 Arvai, A.S, Hitomi, K, Getzoff, E.D. 登録日 2009-10-02 公開日 2009-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural mechanism of abscisic acid binding and signaling by dimeric PYR1. Science, 326, 2009
1CEI	STRUCTURE DETERMINATION OF THE COLICIN E7 IMMUNITY PROTEIN (IMME7) THAT BINDS SPECIFICALLY TO THE DNASE-TYPE COLICIN E7 AND INHIBITS ITS BACTERIOCIDAL ACTIVITY 分子名称: COLICIN E7 IMMUNITY PROTEIN 著者 Chak, K.-F, Safo, M.K, Ku, W.-Y, Hsieh, S.-Y, Yuan, H.S. 登録日 1996-03-19 公開日 1997-03-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The crystal structure of the immunity protein of colicin E7 suggests a possible colicin-interacting surface. Proc.Natl.Acad.Sci.USA, 93, 1996
1S6C	Crystal structure of the complex between KChIP1 and Kv4.2 N1-30 分子名称: CALCIUM ION, Kv4 potassium channel-interacting protein KChIP1b, Potassium voltage-gated channel subfamily D member 2 著者 Zhou, W, Qian, Y, Kunjilwar, K, Pfaffinger, P.J, Choe, S. 登録日 2004-01-23 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels. Neuron, 41, 2004
1RAX	RA-DOMAIN OF RAL GUANOSINE-NUCLEOTIDE DISSOCIATION STIMULATOR 分子名称: PROTEIN (RA-DOMAIN OF RAL GUANOSINE DISSOCIATION STIMULATOR) 著者 Mueller, T.D, Handel, L, Schmieder, P, Oschkinat, H. 登録日 1999-03-13 公開日 1999-03-19 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 High-Resolution Structure of the Ra-Domain of Human Ralgds and a Dynamics Study of its Binding Loop to Ras To be Published
1OVF	NMR Structure of ActD/5'-CCGTTTTGTGG-3' Complex 分子名称: (5'-D(*CP*CP*GP*TP*TP*TP*TP*GP*TP*GP*G)-3'), ACTINOMYCIN D 著者 Chin, K.-H, Chou, S.-H, Chen, F.-M. 登録日 2003-03-26 公開日 2003-05-27 最終更新日 2024-07-10 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Actd-5'-Ccgtt(3)Gtgg-3' Complex: Drug Interaction with Tandem G.T Mismatches and Hairpin Loop Backbone. Nucleic Acids Res., 31, 2003
3RG2	Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis 分子名称: 4'-PHOSPHOPANTETHEINE, 5'-deoxy-5'-({[2-(2-hydroxyphenyl)ethyl]sulfonyl}amino)adenosine, Enterobactin synthase component E (entE), ... 著者 Sundlov, J.A, Gulick, A.M. 登録日 2011-04-07 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains. Chem.Biol., 19, 2012
1FPZ	CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE 分子名称: CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION 著者 Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D. 登録日 2000-09-01 公開日 2001-05-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol.Cell, 7, 2001
4GWV	Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate 分子名称: CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. 登録日 2012-09-03 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallogr.,Sect.D, 69, 2013
3MLQ	Crystal structure of the Thermus thermophilus transcription-repair coupling factor RNA polymerase interacting domain with the Thermus aquaticus RNA polymerase beta1 domain 分子名称: DNA-directed RNA polymerase subunit beta, PHOSPHATE ION, Transcription-repair coupling factor 著者 Darst, S.A, Westblade, L.F, Campbell, E.A. 登録日 2010-04-18 公開日 2010-10-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction. Nucleic Acids Res., 38, 2010
4GWT	Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid 分子名称: (2S)-2-hydroxybutanedioic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T. 登録日 2012-09-03 公開日 2013-10-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallogr.,Sect.D, 69, 2013
8IS2	Crystal structure of a polyketide aromatase/cyclase Abx(+)D from Actinomycetes sp. MA7150. 分子名称: Cyclase 著者 Luo, S, Chen, X. 登録日 2023-03-20 公開日 2024-02-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin. Proc.Natl.Acad.Sci.USA, 121, 2024
3Q7J	Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development 分子名称: L-phenylalanyl-N6-[(benzyloxy)carbonyl]-N1-hydroxy-L-lysinamide, Tricorn protease-interacting factor F3, ZINC ION 著者 Su, J, Wang, Q, Feng, J, Zhang, C, Zhu, D, We, T, Xu, W, Gu, L. 登録日 2011-01-05 公開日 2011-07-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development Bioorg.Med.Chem., 19, 2011
4V1U	Heterocyclase in complex with substrate and Cofactor 分子名称: ADENOSINE MONOPHOSPHATE, CALCIUM ION, LYND, ... 著者 Koehnke, J, Naismith, J.H. 登録日 2014-10-02 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing. Nat.Chem.Biol., 11, 2015
4V1V	Heterocyclase in complex with substrate and Cofactor 分子名称: LYND, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Koehnke, J, Naismith, J.H. 登録日 2014-10-02 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing. Nat.Chem.Biol., 11, 2015
7RRD	IDO1 IN COMPLEX WITH COMPOUND S-1 分子名称: 3-[4-(1H-benzimidazol-2-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide, Indoleamine 2,3-dioxygenase 1 著者 Lesburg, C.A. 登録日 2021-08-09 公開日 2022-08-24 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Oxetane promise delivered: discovery of long acting IDO1 inhibitors suitable for Q3W oral or parenteral dosing To Be Published
4V1T	Heterocyclase in complex with substrate and Cofactor 分子名称: ADENOSINE-5'-DIPHOSPHATE, LYND, MAGNESIUM ION, ... 著者 Koehnke, J, Naismith, J.H. 登録日 2014-10-02 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing Nat.Chem.Biol., 11, 2015
1QTI	Acetylcholinesterase (E.C.3.1.1.7) 分子名称: (-)-GALANTHAMINE, ACETYLCHOLINESTERASE 著者 Bartolucci, C, Perola, E, Pilger, C, Fels, G, Lamba, D. 登録日 1999-06-28 公開日 1999-12-29 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs Proteins, 42, 2001
4EQF	Trip8b-1a#206-567 interacting with the carboxy-terminal seven residues of HCN2 分子名称: PEX5-related protein, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Bankston, J.R, Camp, S.S, Dimaio, F, Lewis, A.S, Chetkovich, D.M, Zagotta, W.N. 登録日 2012-04-18 公開日 2012-05-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. Proc.Natl.Acad.Sci.USA, 109, 2012

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