4GWT
Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid
Summary for 4GWT
Entry DOI | 10.2210/pdb4gwt/pdb |
Related | 2IDH 2KCF 4GWV |
Descriptor | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, (2S)-2-hydroxybutanedioic acid (3 entities in total) |
Functional Keywords | racemic crystallization, ww domain, proline phosphoser/thr binding, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q13526 |
Total number of polymer chains | 1 |
Total formula weight | 4308.73 |
Authors | Mortenson, D.E.,Yun, H.G.,Gellman, S.H.,Forest, K.T. (deposition date: 2012-09-03, release date: 2013-10-16, Last modification date: 2023-09-13) |
Primary citation | Mortenson, D.E.,Kreitler, D.F.,Yun, H.G.,Gellman, S.H.,Forest, K.T. Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallogr.,Sect.D, 69:2506-2512, 2013 Cited by PubMed: 24311591DOI: 10.1107/S090744491302444X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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