PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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4JDS	SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine 分子名称: Histone-lysine N-methyltransferase SETD7, N-[(2R)-3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl]-8-fluoro-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, S-ADENOSYLMETHIONINE, ... 著者 Dong, A, Wu, H, Zeng, H, Park, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2013-02-25 公開日 2013-03-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine to be published
3CBS	CELLULAR RETINOIC ACID BINDING PROTEIN II IN COMPLEX WITH A SYNTHETIC RETINOIC ACID (RO-12 7310) 分子名称: (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid, PROTEIN (CRABP-II) 著者 Chaudhuri, B, Kleywegt, G.J, Bergfors, T, Jones, T.A. 登録日 1999-02-22 公開日 1999-12-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids. Acta Crystallogr.,Sect.D, 55, 1999
3BRI	Crystal Structure of apo-LC8 分子名称: ACETATE ION, Dynein light chain 1, cytoplasmic, ... 著者 Benison, G, Karplus, P.A, Barbar, E, Chiodo, M. 登録日 2007-12-21 公開日 2008-12-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Interplay of Ligand Binding and Quaternary Structure in the Diverse Interactions of Dynein Light Chain LC8. J.Mol.Biol., 384, 2008
4J6Y	Hfq from Pseudomonas aeruginosa crystallized in GTP presence 分子名称: CADMIUM ION, Protein hfq 著者 Nikulin, A.D, Murina, V, Lekontseva, N. 登録日 2013-02-12 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1405 Å) 主引用文献 Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
3CDU	Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. 登録日 2008-02-27 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
7JVX	Crystal structure of PTEN (aa 7-353 followed by spacer TGGGSGGTGGGSGGTGGGCY ligated to peptide pSDpTpTDpSDPENEPFDED) 分子名称: PHOSPHATE ION, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 著者 Dempsey, D, Phan, K, Cole, P, Gabelli, S.B. 登録日 2020-08-24 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structural basis of PTEN regulation by multi-site phosphorylation. Nat.Struct.Mol.Biol., 28, 2021
4N7P	Capturing the haemoglobin allosteric transition in a single crystal form; Crystal structure of half-liganded human haemoglobin without phosphate at 2.8 A resolution. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sugiyama, K, Shibayama, N, Park, S.Y. 登録日 2013-10-16 公開日 2014-04-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.809 Å) 主引用文献 Capturing the hemoglobin allosteric transition in a single crystal form J.Am.Chem.Soc., 136, 2014
3CE4	Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Crichlow, G.V, Lolis, E. 登録日 2008-02-28 公開日 2008-12-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48, 2009
3CDW	Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. 登録日 2008-02-27 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
3AO2	Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase 分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-(7-bromo-1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazol-5-amine, ... 著者 Wielens, J, Chalmers, D.K, Headey, S.J, Parker, M.W, Scanlon, M.J. 登録日 2010-09-20 公開日 2011-03-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
4J2L	Crystal Structure of AXH domain complexed with Capicua 分子名称: Ataxin-1, Protein capicua homolog 著者 Song, J.-J, Kim, E. 登録日 2013-02-04 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua Genes Dev., 27, 2013
4JLI	Crystal Structure of Escherichia coli Hfq Proximal Pore Mutant 分子名称: Protein hfq 著者 Robinson, K.E, Orans, J. 登録日 2013-03-12 公開日 2013-12-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching. Nucleic Acids Res., 42, 2014
2F69	Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide 分子名称: Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Couture, J.-F, Collazo, E, Hauk, G, Trievel, R.C. 登録日 2005-11-28 公開日 2006-01-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural basis for the methylation site specificity of SET7/9 Nat.Struct.Mol.Biol., 13, 2006
2F8E	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein 分子名称: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-12-02 公開日 2006-03-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
4OK7	Structure of bacteriophage SPN1S endolysin from Salmonella typhimurium 分子名称: Endolysin, GLYCEROL, SULFATE ION 著者 Park, Y, Lim, J, Kong, M, Ryu, S, Rhee, S. 登録日 2014-01-22 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of bacteriophage SPN1S endolysin reveals an unusual two-module fold for the peptidoglycan lytic and binding activity. Mol.Microbiol., 92, 2014
4JLU	Crystal structure of BRCA1 BRCT with doubly phosphorylated Abraxas 分子名称: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein 著者 Badgujar, D, Varma, A.K. 登録日 2013-03-13 公開日 2014-09-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of BRCA1 BRCT with doubly phosphorylated Abraxas To be Published
4J6W	Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP 分子名称: CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, ... 著者 Nikulin, A.D, Murina, V, Lekontseva, N. 登録日 2013-02-12 公開日 2013-07-31 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
4J7F	SET7/9Y335pAF in complex with TAF10 peptide and AdoHcy 分子名称: Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, Transcription initiation factor TFIID subunit 10 著者 Horowitz, S, Del Rizzo, P.A, Trievel, R.C. 登録日 2013-02-13 公開日 2014-03-26 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Methyl CH O Hydrogen Bonds Orchestrate AdoMet-Dependent Methylation To be Published
4JUV	Crystal Structure of Escherichia coli Hfq Distal Face 1 Mutant 分子名称: Protein hfq 著者 Robinson, K.E, Orans, J. 登録日 2013-03-25 公開日 2013-12-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching. Nucleic Acids Res., 42, 2014
4J7I	SET7/9Y335F in complex with TAF10 peptide and AdoHcy 分子名称: Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, Transcription initiation factor TFIID subunit 10 著者 Horowitz, S, Trievel, R.C. 登録日 2013-02-13 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases. J.Am.Chem.Soc., 135, 2013
4J83	SET7/9 in complex with TAF10K189A peptide and AdoMet 分子名称: Histone-lysine N-methyltransferase SETD7, S-ADENOSYLMETHIONINE, Transcription initiation factor TFIID subunit 10 著者 Horowitz, S, Nimtz, J.S, Trievel, R.C. 登録日 2013-02-14 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases. J.Am.Chem.Soc., 135, 2013
4N7N	Capturing the haemoglobin allosteric transition in a single crystal form; Crystal structure of full-liganded human haemoglobin with phosphate at 2.75 A resolution. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugiyama, K, Shibayama, N, Park, S.Y. 登録日 2013-10-16 公開日 2014-04-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.754 Å) 主引用文献 Capturing the hemoglobin allosteric transition in a single crystal form J.Am.Chem.Soc., 136, 2014
3AO1	Fragment-based approach to the design of ligands targeting a novel site in HIV-1 integrase 分子名称: 1,3-benzodioxol-5-ol, CADMIUM ION, POL polyprotein, ... 著者 Wielens, J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. 登録日 2010-09-17 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
4HT8	Crystal structure of E coli Hfq bound to poly(A) A7 分子名称: Protein hfq, RNA (5'-R(*AP*AP*AP*AP*AP*AP*A)-3') 著者 Wang, W.W, Wang, L.J. 登録日 2012-11-01 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA. Nucleic Acids Res., 41, 2013
2F5J	Crystal structure of MRG domain from human MRG15 分子名称: Mortality factor 4-like protein 1 著者 Zhang, P, Du, J, Ding, J. 登録日 2005-11-26 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14 Protein Sci., 15, 2006

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