2F69

Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide

Summary for 2F69

• Entry DOI: 10.2210/pdb2f69/pdb
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, TAF10 peptide, Acetyl-Ser-Lys-Ser-Mlz-Asp-Arg-Lys-Tyr-Thr-Leu, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: set domain, protein lysine methyltransferase, enzyme-peptide-adohcy complex, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q8WTS6
• Total number of polymer chains: 2
• Total formula weight: 30696.23

Authors

Couture, J.-F.,Collazo, E.,Hauk, G.,Trievel, R.C. (deposition date: 2005-11-28, release date: 2006-01-17, Last modification date: 2023-08-23)

• Primary citation: Couture, J.-F.,Collazo, E.,Hauk, G.,Trievel, R.C.; Structural basis for the methylation site specificity of SET7/9; Nat.Struct.Mol.Biol., 13:140-146, 2006; PubMed: 16415881; DOI: 10.1038/nsmb1045

Experimental method

X-RAY DIFFRACTION (1.3 Å)