2F69
Ternary complex of SET7/9 bound to AdoHcy and a TAF10 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 | polymer | 261 | 29043.3 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | Homo sapiens (human) | Histone H3-K4 methyltransferase, H3-K4-HMTase, SET domain-containing protein 7, Set9, SET7/9 |
| 2 | B (B) | TAF10 peptide, Acetyl-Ser-Lys-Ser-Mlz-Asp-Arg-Lys-Tyr-Thr-Leu | polymer | 11 | 1268.5 | 1 | UniProt (by SIFTS) (Q12962) | ||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 472 | Chemie (HOH) |
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | cloning artifact |
| Ala 107 | - | cloning artifact |
| Met 108 | - | cloning artifact |
| Gly 109 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30311.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 30696.2 |
