4W6K
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7E0F
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4V5S
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![BU of 4v5s by Molmil](/molmil-images/mine/4v5s) | The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome. | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | 登録日 | 2010-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
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2YJE
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![BU of 2yje by Molmil](/molmil-images/mine/2yje) | Oligomeric assembly of actin bound to MRTF-A | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Mouilleron, S, Langer, C.A, Guettler, S, McDonald, N.Q, Treisman, R. | 登録日 | 2011-05-19 | 公開日 | 2011-07-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator. Sci Signal, 4, 2011
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8U7U
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![BU of 8u7u by Molmil](/molmil-images/mine/8u7u) | Proteasome 20S Core Particle from Beta 3 D205 deletion | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | 登録日 | 2023-09-15 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.16 Å) | 主引用文献 | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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2W4U
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![BU of 2w4u by Molmil](/molmil-images/mine/2w4u) | Isometrically contracting insect asynchronous flight muscle quick frozen after a length step | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ... | 著者 | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | 登録日 | 2008-12-02 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (35 Å) | 主引用文献 | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation. Plos One, 7, 2012
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8U6Y
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![BU of 8u6y by Molmil](/molmil-images/mine/8u6y) | Preholo-Proteasome from Beta 3 D205 deletion | 分子名称: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | 著者 | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | 登録日 | 2023-09-14 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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8UC8
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![BU of 8uc8 by Molmil](/molmil-images/mine/8uc8) | HCN1 nanodisc | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | 著者 | Kim, E.D, Nimigean, C.M. | 登録日 | 2023-09-25 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature, 2024
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8UC7
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![BU of 8uc7 by Molmil](/molmil-images/mine/8uc7) | HCN1 complex with propofol | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,6-BIS(1-METHYLETHYL)PHENOL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | 著者 | Kim, E.D, Nimigean, C.M. | 登録日 | 2023-09-25 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature, 2024
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8W22
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![BU of 8w22 by Molmil](/molmil-images/mine/8w22) | Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1) | 分子名称: | Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein | 著者 | Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D. | 登録日 | 2024-02-19 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Streptomyces umbrella toxin particles block hyphal growth of competing species. Nature, 629, 2024
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8W83
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![BU of 8w83 by Molmil](/molmil-images/mine/8w83) | HLA-DQ2.5-alpha1 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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2VUX
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![BU of 2vux by Molmil](/molmil-images/mine/2vux) | Human ribonucleotide reductase, subunit M2 B | 分子名称: | FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B | 著者 | Welin, M, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2008-05-31 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human Ribonucleotide Reductase, Subunit M2 B To be Published
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2W49
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![BU of 2w49 by Molmil](/molmil-images/mine/2w49) | ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, CALCIUM ION, ... | 著者 | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | 登録日 | 2008-11-24 | 公開日 | 2010-05-05 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (35 Å) | 主引用文献 | Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions Plos One, 5, 2010
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8W20
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![BU of 8w20 by Molmil](/molmil-images/mine/8w20) | Umb1 umbrella toxin particle | 分子名称: | Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein | 著者 | Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D. | 登録日 | 2024-02-19 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Streptomyces umbrella toxin particles block hyphal growth of competing species. Nature, 629, 2024
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7F5K
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![BU of 7f5k by Molmil](/molmil-images/mine/7f5k) | Crystal structure of TCR4-1 ectodomain | 分子名称: | T cell receptor alpha chain, T cell receptor beta chain | 著者 | Nagae, M, Yamasaki, S. | 登録日 | 2021-06-22 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.0000298 Å) | 主引用文献 | Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b. Nat Commun, 13, 2022
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8W0S
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![BU of 8w0s by Molmil](/molmil-images/mine/8w0s) | Human EBP complexed with compound 3a | 分子名称: | 1-methyl-8-[(oxan-4-yl)methyl]-3-[4-(trifluoromethyl)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | 著者 | Sun, D, Masureel, M. | 登録日 | 2024-02-14 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. J.Med.Chem., 67, 2024
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8W0R
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![BU of 8w0r by Molmil](/molmil-images/mine/8w0r) | Human EBP complexed with compound 1 | 分子名称: | 1-methyl-1'-[(oxan-4-yl)methyl]-5-(trifluoromethyl)spiro[indole-2,4'-piperidin]-3(1H)-one, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | 著者 | Sun, D, Masureel, M. | 登録日 | 2024-02-14 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation. J.Med.Chem., 67, 2024
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1HDT
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1HAP
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![BU of 1hap by Molmil](/molmil-images/mine/1hap) | COMPLEX OF HUMAN ALPHA-THROMBIN WITH A 15MER OLIGONUCLEOTIDE GGTTGGTGTGGTTGG (BASED ON X-RAY MODEL OF DNA) | 分子名称: | 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3', D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... | 著者 | Padmanabhan, K, Tulinsky, A. | 登録日 | 1995-10-03 | 公開日 | 1996-04-03 | 最終更新日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An ambiguous structure of a DNA 15-mer thrombin complex. Acta Crystallogr.,Sect.D, 52, 1996
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7D80
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![BU of 7d80 by Molmil](/molmil-images/mine/7d80) | Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase, trigger factor, and methionine aminopeptidase | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Akbar, S, Bhakta, S, Sengupta, J. | 登録日 | 2020-10-06 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into the interplay of protein biogenesis factors with the 70S ribosome. Structure, 29, 2021
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2V51
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![BU of 2v51 by Molmil](/molmil-images/mine/2v51) | Structure of MAL-RPEL1 complexed to actin | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q. | 登録日 | 2008-10-01 | 公開日 | 2008-11-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J., 27, 2008
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8WKY
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![BU of 8wky by Molmil](/molmil-images/mine/8wky) | Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with S25 | 分子名称: | CALCIUM ION, Melanocortin receptor 4, N-(2-aminoethyl)-5-(2-{[4-(morpholin-4-yl)pyridin-2-yl]amino}-1,3-thiazol-5-yl)pyridine-3-carboxamide, ... | 著者 | Gimenez, L.E, Martin, C, Yu, J, Hollanders, C, Hernandez, C, Dahir, N.S, Wu, Y, Yao, D, Han, G.W, Wu, L, Poorten, O.V, Lamouroux, A, Mannes, M, Tourwe, D, Zhao, S, Stevens, R.C, Cone, R.D, Ballet, S. | 登録日 | 2023-09-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. J.Med.Chem., 67, 2024
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2VYP
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![BU of 2vyp by Molmil](/molmil-images/mine/2vyp) | Rabbit-muscle G-actin in complex with myxobacterial rhizopodin | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Hagelueken, G, Albrecht, S.C, Steinmetz, H, Jansen, R, Heinz, D.W, Kalesse, M, Schubert, W.-D. | 登録日 | 2008-07-25 | 公開日 | 2009-02-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The Absolute Configuration of Rhizopodin and its Inhibition of Actin Polymerization by Dimerization. Angew.Chem.Int.Ed.Engl., 48, 2009
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8WKZ
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![BU of 8wkz by Molmil](/molmil-images/mine/8wkz) | Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with S31 | 分子名称: | CALCIUM ION, Melanocortin receptor 4, OLEIC ACID, ... | 著者 | Gimenez, L.E, Martin, C, Yu, J, Hollanders, C, Hernandez, C, Dahir, N.S, Wu, Y, Yao, D, Han, G.W, Wu, L, Poorten, O.V, Lamouroux, A, Mannes, M, Tourwe, D, Zhao, S, Stevens, R.C, Cone, R.D, Ballet, S. | 登録日 | 2023-09-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. J.Med.Chem., 67, 2024
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8YXN
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