1HDT

STRUCTURE OF A RETRO-BINDING PEPTIDE INHIBITOR COMPLEXED WITH HUMAN ALPHA-THROMBIN

Summary for 1HDT
Related PRD IDPRD_000254
DescriptorALPHA-THROMBIN, HIRUGEN PEPTIDE, methyl N-(4-carbamimidamidobutanoyl)-L-phenylalanyl-L-allothreonyl-L-phenylalaninate, ... (5 entities in total)
Functional Keywordsserine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHirudo medicinalis (Medicinal leech)
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Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P28507
Total number of polymer chains3
Total formula weight35674.64
Authors
Tabernero, L.,Sack, J. (deposition date: 1994-07-25, release date: 1995-10-15, Last modification date: 2012-12-12)
Primary citationChang, C.Y.,Han, W.C.,Iwanowicz, E.J.,Lau, W.F.,Ohringer, S.L.,Roberts, D.G.,Sack, J.S.,Seiler, S.M.,Tabernero, L.,Wang, T.C.
Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin.
J.Mol.Biol., 246:14-20, 1995
PubMed: 7853394
DOI: 110.1006/jmbi.1994.0060
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation
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PDB entries from 2021-06-16