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8P16
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E167K RF2 on E. coli 70S release complex with UGG (Structure I)
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S.
登録日2023-05-11
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria
To Be Published
8P17
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BU of 8p17 by Molmil
E167K RF2 on E. coli 70S release complex with UGG (Structure II)
分子名称: 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ...
著者Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S.
登録日2023-05-11
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria
To Be Published
8R62
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BU of 8r62 by Molmil
Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
8R8P
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BU of 8r8p by Molmil
Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition
分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-6-(4-methylpiperazin-1-yl)quinazoline, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-29
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLID-STATE NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
8R63
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Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 5-(1~{H}-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
7LR2
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BU of 7lr2 by Molmil
Crystal structure of GH5_18 from Bifidobacterium longum subsp. longum ATCC 55813 in complex with GlcNAc
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyl hydrolase BlGH5_18, ...
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-15
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
7LR7
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BU of 7lr7 by Molmil
Crystal structure of GH5_18 from Streptomyces cattleya in complex with GlcNAc
分子名称: 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-16
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
7LR6
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BU of 7lr6 by Molmil
Crystal structure of GH5_18-E140A from Bifidobacterium longum subsp. longum ATCC 55813 in complex with Manb1-4GlcNAc
分子名称: Glycosyl hydrolase BlGH5_18, PHOSPHATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-16
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
7LQX
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BU of 7lqx by Molmil
Crystal structure of a GH5_18 from Bifidobacterium longum subsp. infantis
分子名称: 1,2-ETHANEDIOL, Glycosyl hydrolase BlGH5_18, SULFATE ION
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-15
公開日2021-04-07
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
7LR1
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BU of 7lr1 by Molmil
Crystal structure of GH5_18 from Bifidobacterium longum subsp. longum ATCC 55813
分子名称: 1,2-ETHANEDIOL, Glycosyl hydrolase BlGH5_18, PHOSPHATE ION
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-15
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
7LR8
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BU of 7lr8 by Molmil
Crystal structure of GH5_18-E153A from Streptomyces cattleya in complex with Manb1-4GlcNAc
分子名称: 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, SULFATE ION, ...
著者Higgins, M.A, Ryan, K.S.
登録日2021-02-16
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes.
Acs Chem.Biol., 16, 2021
6Z9C
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BU of 6z9c by Molmil
Structure of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability
分子名称: Polymerase delta-interacting protein 2, SODIUM ION
著者Kulik, A.A, Maruszczak, K, Nabi, N.L.M, Bingham, R.J, Cooper, C.D.O.
登録日2020-06-03
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability.
Protein Sci., 30, 2021
1CEI
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BU of 1cei by Molmil
STRUCTURE DETERMINATION OF THE COLICIN E7 IMMUNITY PROTEIN (IMME7) THAT BINDS SPECIFICALLY TO THE DNASE-TYPE COLICIN E7 AND INHIBITS ITS BACTERIOCIDAL ACTIVITY
分子名称: COLICIN E7 IMMUNITY PROTEIN
著者Chak, K.-F, Safo, M.K, Ku, W.-Y, Hsieh, S.-Y, Yuan, H.S.
登録日1996-03-19
公開日1997-03-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of the immunity protein of colicin E7 suggests a possible colicin-interacting surface.
Proc.Natl.Acad.Sci.USA, 93, 1996
1OVF
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BU of 1ovf by Molmil
NMR Structure of ActD/5'-CCGTTTTGTGG-3' Complex
分子名称: (5'-D(*CP*CP*GP*TP*TP*TP*TP*GP*TP*GP*G)-3'), ACTINOMYCIN D
著者Chin, K.-H, Chou, S.-H, Chen, F.-M.
登録日2003-03-26
公開日2003-05-27
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Actd-5'-Ccgtt(3)Gtgg-3' Complex: Drug Interaction with Tandem G.T Mismatches and Hairpin Loop Backbone.
Nucleic Acids Res., 31, 2003
8DOV
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BU of 8dov by Molmil
Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin
分子名称: GLYCEROL, Heme-binding protein Shr, Hemoglobin subunit alpha, ...
著者Macdonald, R, Mahoney, B.J, Cascio, D, Clubb, R.T.
登録日2022-07-14
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin.
Proc.Natl.Acad.Sci.USA, 120, 2023
1FPZ
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BU of 1fpz by Molmil
CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE
分子名称: CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION
著者Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D.
登録日2000-09-01
公開日2001-05-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
Mol.Cell, 7, 2001
1S6C
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BU of 1s6c by Molmil
Crystal structure of the complex between KChIP1 and Kv4.2 N1-30
分子名称: CALCIUM ION, Kv4 potassium channel-interacting protein KChIP1b, Potassium voltage-gated channel subfamily D member 2
著者Zhou, W, Qian, Y, Kunjilwar, K, Pfaffinger, P.J, Choe, S.
登録日2004-01-23
公開日2004-02-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels.
Neuron, 41, 2004
1FWQ
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BU of 1fwq by Molmil
SOLUTION STRUCTURE OF HUMAN MSS4, A GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB PROTEINS
分子名称: GUANINE NUCLEOTIDE EXCHANGE FACTOR, ZINC ION
著者Yu, H, Schreiber, S.L.
登録日2000-09-24
公開日2000-10-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface.
Nature, 376, 1995
5IT3
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BU of 5it3 by Molmil
Swirm domain of human Lsd1
分子名称: Lysine-specific histone demethylase 1A, MAGNESIUM ION
著者Jeffrey, P.D, Yuan, P.
登録日2016-03-16
公開日2016-05-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells
To Be Published
4AIF
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BU of 4aif by Molmil
AIP TPR domain in complex with human Hsp90 peptide
分子名称: AH RECEPTOR-INTERACTING PROTEIN, HEAT SHOCK PROTEIN HSP 90-ALPHA, SULFATE ION
著者Morgan, R.M.L, Roe, S.M, Pearl, L.H, Prodromou, C.
登録日2012-02-09
公開日2013-01-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition.
Plos One, 7, 2012
4APO
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BU of 4apo by Molmil
AIP TPR domain in complex with human Tomm20 peptide
分子名称: AH RECEPTOR-INTERACTING PROTEIN, DODECAETHYLENE GLYCOL, MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG, ...
著者Morgan, R.M.L, Roe, S.M, Pearl, L.H, Prodromou, C.
登録日2012-04-04
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Structure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition.
Plos One, 7, 2012
4GWV
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BU of 4gwv by Molmil
Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate
分子名称: CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T.
登録日2012-09-03
公開日2013-10-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
6MNI
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BU of 6mni by Molmil
Structure of the tandem CACHE domain of PscC
分子名称: CHLORIDE ION, GLYCEROL, Methyl-accepting chemotaxis protein, ...
著者Johnston, J.M, Gerth, M.L, Ehrhardt, M.K.G.
登録日2018-10-01
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Structure of a double CACHE chemoreceptor ligand-binding domain from Pseudomonas syringae provides insights into the basis of proline recognition.
Biochem.Biophys.Res.Commun., 549, 2021
8IS2
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BU of 8is2 by Molmil
Crystal structure of a polyketide aromatase/cyclase Abx(+)D from Actinomycetes sp. MA7150.
分子名称: Cyclase
著者Luo, S, Chen, X.
登録日2023-03-20
公開日2024-02-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin.
Proc.Natl.Acad.Sci.USA, 121, 2024
5WB5
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BU of 5wb5 by Molmil
Leishmania IF4E-1 bound to Leishmania 4E-IP1
分子名称: DI(HYDROXYETHYL)ETHER, Putative eukaryotic translation initiation factor eIF-4E, Uncharacterized protein
著者Leger-Abraham, M, Meleppattu, S, Arthanari, H, Zinoviev, A, Boeszoermenyi, A, Wagner, G, Shapira, M.
登録日2017-06-27
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Nucleic Acids Res., 46, 2018

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件を2024-07-03に公開中

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