8DOV
Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin
Summary for 8DOV
Entry DOI | 10.2210/pdb8dov/pdb |
Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, Heme-binding protein Shr, ... (6 entities in total) |
Functional Keywords | duf1533, hemoglobin, heme, hid, complex, beta-sandwich, globin, shr, transport protein |
Biological source | Streptococcus pyogenes More |
Total number of polymer chains | 11 |
Total formula weight | 166414.19 |
Authors | Macdonald, R.,Mahoney, B.J.,Cascio, D.,Clubb, R.T. (deposition date: 2022-07-14, release date: 2023-01-25, Last modification date: 2023-10-25) |
Primary citation | Macdonald, R.,Mahoney, B.J.,Soule, J.,Goring, A.K.,Ford, J.,Loo, J.A.,Cascio, D.,Clubb, R.T. The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin. Proc.Natl.Acad.Sci.USA, 120:e2211939120-e2211939120, 2023 Cited by PubMed: 36693107DOI: 10.1073/pnas.2211939120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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