8DOV

Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin

Summary for 8DOV

Entry DOI	10.2210/pdb8dov/pdb
Descriptor	Hemoglobin subunit alpha, Hemoglobin subunit beta, Heme-binding protein Shr, ... (6 entities in total)
Functional Keywords	duf1533, hemoglobin, heme, hid, complex, beta-sandwich, globin, shr, transport protein
Biological source	Streptococcus pyogenes More
Total number of polymer chains	11
Total formula weight	166414.19
Authors	Macdonald, R.,Mahoney, B.J.,Cascio, D.,Clubb, R.T. (deposition date: 2022-07-14, release date: 2023-01-25, Last modification date: 2023-10-25)
Primary citation	Macdonald, R.,Mahoney, B.J.,Soule, J.,Goring, A.K.,Ford, J.,Loo, J.A.,Cascio, D.,Clubb, R.T. The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin. Proc.Natl.Acad.Sci.USA, 120:e2211939120-e2211939120, 2023 Cited by PubMed: 36693107 DOI: 10.1073/pnas.2211939120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation