PDB: 37819 件ウェブページステータス検索Chemie searchBIRD

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6Q8A	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine 分子名称: 5'-O-(N-(L-Leucyl)-Sulfamoyl)Cytidine, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
8IHN	Cryo-EM structure of the Rpd3S core complex 分子名称: CALCIUM ION, Chromatin modification-related protein EAF3, Histone H3, ... 著者 Zhang, Y, Gang, C. 登録日 2023-02-23 公開日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme. Cell Res., 33, 2023
7M1X	Cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z 分子名称: DNA (136-MER), Histone H2A.Z, Histone H2B 1.1, ... 著者 Tan, D, Lewis, T. 登録日 2021-03-15 公開日 2021-09-29 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of chromatin regulation by histone variant H2A.Z. Nucleic Acids Res., 49, 2021
6Q89	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Leucyl)-Sulfamoyl)Adenosine 分子名称: 1,2-ETHANEDIOL, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
3EXM	Crystal structure of the phosphatase SC4828 with the non-hydrolyzable nucleotide GPCP 分子名称: CALCIUM ION, GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID GUANOSYL ESTER, ... 著者 Singer, A.U, Xu, X, Zheng, H, Joachimiak, A, Edwards, A.M, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) 登録日 2008-10-16 公開日 2008-12-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and mechanism of a new family of prokaryotic nucleoside diphosphatases. To be Published
3REK	2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin 分子名称: DNA (146-MER), Histone H2A type1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
4B36	Crystal Structure of Human Angiogenin with an Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule 分子名称: ANGIOGENIN, EOSINOPHIL CATIONIC-RELATED PROTEIN, CHLORIDE ION 著者 Thiyagarajan, N, Acharya, K.R. 登録日 2012-07-20 公開日 2012-12-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal Structure of Human Angiogenin with an Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule FEBS Open Bio., 3, 2012
4P5D	CRYSTAL STRUCTURE OF RAT DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 6-(naphthalen-2-yl)-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine, SULFATE ION 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2014-03-16 公開日 2014-08-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities. Eur.J.Med.Chem., 85C, 2014
6X4D	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(cyclopropylmethyl)-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile (JLJ678), a Non-nucleoside Inhibitor 分子名称: 5-(cyclopropylmethyl)-7-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-8-methylnaphthalene-2-carbonitrile, Reverse transcriptase/ribonuclease H, SULFATE ION, ... 著者 Chan, A.H, Duong, V.N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. 登録日 2020-05-22 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site. Protein Sci., 29, 2020
6Q8C	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)Uridine 分子名称: 1,2-ETHANEDIOL, 5'-O-(N-(L-Leucyl)-Sulfamoyl)Uridine, Leucine--tRNA ligase, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
6Q8B	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)N3-methyluridine 分子名称: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
6UR2	DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template and primer containing an N3'-> P5' linkage 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*(C42)P*G)-3'), DNA (5'-D(P*AP*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I 著者 Zhang, W, Lelyveld, V.S, Szostak, J.W. 登録日 2019-10-21 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
3REJ	2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) 分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
3REL	2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride 分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
4KXM	Crystal structure of DNPH1 (RCL) WITH N6-ISOPENTENYL-AMP 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2013-05-27 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1. Plos One, 8, 2013
3QEX	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite dT 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes To be Published
4KXL	Crystal structure of DNPH1 (RCL) with 6-CYCLOPENTYL-AMP 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N-cyclopentyladenosine 5'-(dihydrogen phosphate), SULFATE ION 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2013-05-27 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1. Plos One, 8, 2013
3REI	2.65 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145) Derivatized with Triamminechloroplatinum(II) Chloride 分子名称: DNA (145-MER), Histone H2A type1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
4KXN	Crystal structure of DNPH1 (RCL) with kinetine riboside monophosphate 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N-(furan-2-ylmethyl)adenosine 5'-(dihydrogen phosphate) 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2013-05-27 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1. Plos One, 8, 2013
3REH	2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145) 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2011-04-04 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. Nucleic Acids Res., 39, 2011
1SYX	The crystal structure of a binary U5 snRNP complex 分子名称: CD2 antigen cytoplasmic tail-binding protein 2, Spliceosomal U5 snRNP-specific 15 kDa protein 著者 Nielsen, T.K, Liu, S, Luhrmann, R, Ficner, R. 登録日 2004-04-02 公開日 2005-10-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.345 Å) 主引用文献 Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). J.Mol.Biol., 369, 2007
3WA9	The nucleosome containing human H2A.Z.1 分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... 著者 Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. 登録日 2013-04-30 公開日 2013-12-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
6U3R	Solution NMR structure of the DNAJB6b deltaST variant (Aligned on the J domain) 分子名称: DnaJ homolog subfamily B member 6,DnaJ homolog subfamily B member 6 著者 Karamanos, T.K, Clore, G.M. 登録日 2019-08-22 公開日 2019-10-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis. Proc.Natl.Acad.Sci.USA, 116, 2019
4P5E	CRYSTAL STRUCTURE OF HUMAN DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 6-(naphthalen-2-yl)-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine, CALCIUM ION 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2014-03-16 公開日 2014-08-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities. Eur.J.Med.Chem., 85C, 2014
4P5F	The crystal structure of type III effector protein XopQ complexed with adenosine diphosphate ribose 分子名称: CALCIUM ION, Inosine-uridine nucleoside N-ribohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Yu, S, Hwang, I, Rhee, S. 登録日 2014-03-17 公開日 2014-08-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of type III effector protein XopQ from Xanthomonas oryzae complexed with adenosine diphosphate ribose. Proteins, 82, 2014

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