PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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7UNE	The V1 region of bovine V-ATPase in complex with human mEAK7 (focused refinement) 分子名称: KIAA1609 protein, isoform CRA_a, V-type proton ATPase catalytic subunit A, ... 著者 Wang, R, Li, X. 登録日 2022-04-10 公開日 2022-06-15 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.73 Å) 主引用文献 Molecular basis of mEAK7-mediated human V-ATPase regulation. Nat Commun, 13, 2022
7LYX	Crystal structure of human CYP8B1 in complex with (S)-tioconazole 分子名称: (S)-Tioconazole, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, GLYCEROL, ... 著者 Liu, J, Scott, E.E. 登録日 2021-03-08 公開日 2022-08-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes. J.Biol.Chem., 298, 2022
7B9P	Structure of Ribonucleotide reductase from Rhodobacter sphaeroides 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase 著者 Wilk, P, Feiler, C, Loderer, C, Kabinger, F. 登録日 2020-12-14 公開日 2022-01-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.646 Å) 主引用文献 HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry, 61, 2022
3HXC	Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 8) 分子名称: CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... 著者 Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. 登録日 2009-06-20 公開日 2009-09-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors J.Med.Chem., 52, 2009
3ATP	Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr with ligand 分子名称: Methyl-accepting chemotaxis protein I, SERINE 著者 Tajima, H, Sakuma, M, Homma, K, Kawagishi, I, Imada, K. 登録日 2011-01-07 公開日 2011-10-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Ligand specificity determined by differentially arranged common ligand-binding residues in bacterial amino acid chemoreceptors Tsr and Tar. J.Biol.Chem., 286, 2011
5M50	Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins 分子名称: Calmodulin-regulated spectrin-associated protein 3, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-P, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. 登録日 2016-10-20 公開日 2017-10-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
7RKC	Computationally designed tunable C2 symmetric tandem repeat homodimer, D_3_633 分子名称: ACETATE ION, D_3_633 著者 Kennedy, M.A, Stoddard, B.L, Hicks, D.R, Bera, A.K. 登録日 2021-07-22 公開日 2022-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 De novo design of protein homodimers containing tunable symmetric protein pockets. Proc.Natl.Acad.Sci.USA, 119, 2022
5M2Z	Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) 分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. 登録日 2016-10-13 公開日 2018-06-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4.8 Å) 主引用文献 Supramolecular arrangement of the full-length Zika virus NS5. Plos Pathog., 15, 2019
7DBL	Acyl-CoA hydrolase MpaH' mutant S139A in complex with MPA 分子名称: MYCOPHENOLIC ACID, acyl-CoA hydrolase MpaH' 著者 Li, S.Y, You, C. 登録日 2020-10-20 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis. Febs J., 288, 2021
3HX0	ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', 5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3', ... 著者 Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Havener, J.M, Perera, L, Krahn, J.M, Pedersen, L.C, Ramsden, D.A, Kunkel, T.A. 登録日 2009-06-19 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Scrunching During DNA Repair Synthesis To be Published
7LL7	[2]Catenane From MccJ25 Variant G12C G21C 分子名称: GLY-GLY-ALA-GLY-HIS-VAL-PRO-GLU-TYR-PHE, VAL-CYS-ILE-GLY-THR-PRO-ILE-SER-PHE-TYR-CYS 著者 Link, A.J, Schroeder, H.V. 登録日 2021-02-03 公開日 2021-08-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides. Nat.Chem., 13, 2021
7D34	AtClpS1-peptide complex 分子名称: ACETIC ACID, ALANINE, ATP-dependent Clp protease adapter protein CLPS1, ... 著者 Heo, J, Kim, L, Kwon, D.H, Song, H.K. 登録日 2020-09-18 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.007 Å) 主引用文献 Structural basis for the N-degron specificity of ClpS1 from Arabidopsis thaliana. Protein Sci., 30, 2021
5M3Z	Crystal structure of Citrobacter freundii methionine gamma-lyase with C115H replacement in the complex with L-norleucine 分子名称: 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC ACID, Methionine gamma-lyase, NORLEUCINE, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2016-10-17 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of mutant form Cys115His of Citrobacter freundii methionine gamma-lyase complexed with l-norleucine. Biochim. Biophys. Acta, 1865, 2017
7D72	Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose 分子名称: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, Mannose-1-phosphate guanyltransferase alpha, ... 著者 Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. 登録日 2020-10-02 公開日 2021-05-05 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
5M4Z	Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate 分子名称: GLYCEROL, Thymidylate synthase, [(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate 著者 Wilk, P, Maj, P, Jarmula, A, Dowiercial, A, Rode, W. 登録日 2016-10-19 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.179 Å) 主引用文献 Molecular Mechanism of Thymidylate Synthase Inhibition by N 4 -Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies. Int J Mol Sci, 22, 2021
2K46	Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc) 分子名称: MGC80075 protein, alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose 著者 Schallus, T. 登録日 2008-05-28 公開日 2008-08-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation Mol.Cell.Biol., 19, 2008
3HXF	Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32) 分子名称: CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... 著者 Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. 登録日 2009-06-20 公開日 2009-09-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors J.Med.Chem., 52, 2009
7D73	Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) 分子名称: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, ... 著者 Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. 登録日 2020-10-02 公開日 2021-05-05 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat.Struct.Mol.Biol., 28, 2021
7DQ7	Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5 分子名称: 5F5 VH, 5F5 VL, Capsid protein VP4, ... 著者 Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. 登録日 2020-12-22 公開日 2021-05-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
7DQ4	Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle 分子名称: VP2, VP3, Virion protein 1 著者 Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. 登録日 2020-12-22 公開日 2021-05-05 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
5M4Q	Crystal Structure of Wild-Type Human Prolidase with Mn ions and Pro ligand 分子名称: GLYCEROL, HYDROXIDE ION, MANGANESE (II) ION, ... 著者 Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. 登録日 2016-10-18 公開日 2017-07-12 最終更新日 2020-04-22 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Substrate specificity and reaction mechanism of human prolidase. FEBS J., 284, 2017
7REW	Crystal Structure of IL-13 in complex with MMAb3 Fab 分子名称: IL13, anti-cyno interleukin 13 Fab heavy chain, anti-cyno interleukin 13 Fab light chain 著者 Sudom, A, Min, X. 登録日 2021-07-13 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation. J.Biol.Chem., 298, 2022
7DNC	Crystal structure of EV71 3C proteinase in complex with a novel inhibitor 分子名称: 3C protease, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide 著者 Xie, H, Su, H.X, Li, M.J, Xu, Y.C. 登録日 2020-12-09 公開日 2021-05-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J.Med.Chem., 65, 2022
3ASK	Structure of UHRF1 in complex with histone tail 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION 著者 Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. 登録日 2010-12-16 公開日 2012-01-25 最終更新日 2013-06-05 実験手法 X-RAY DIFFRACTION (2.904 Å) 主引用文献 Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012
7DPG	Cryo-EM structure of Coxsackievirus B1 empty particle 分子名称: VP2, VP3, Virion protein 1 著者 Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N. 登録日 2020-12-18 公開日 2021-05-05 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021

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