3HX0

ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA

Summary for 3HX0

• Entry DOI: 10.2210/pdb3hx0/pdb
• Related: 3HW8 3HWT
• Descriptor: DNA polymerase lambda, 5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3', 5'-D(*CP*AP*GP*TP*AP*T)-3', ... (8 entities in total)
• Functional Keywords: scrunch, x-family, polymerase lambda, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, manganese, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, polymorphism, transferase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q9UGP5
• Total number of polymer chains: 16
• Total formula weight: 177772.41

Authors

Garcia-Diaz, M.,Bebenek, K.,Larrea, A.A.,Havener, J.M.,Perera, L.,Krahn, J.M.,Pedersen, L.C.,Ramsden, D.A.,Kunkel, T.A. (deposition date: 2009-06-19, release date: 2009-08-25, Last modification date: 2023-09-06)

• Primary citation: Garcia-Diaz, M.,Bebenek, K.,Larrea, A.A.,Havener, J.M.,Perera, L.,Krahn, J.M.,Pedersen, L.C.,Ramsden, D.A.,Kunkel, T.A.; Scrunching During DNA Repair Synthesis; To be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)