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8JDM
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Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDL
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Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDK
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Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDJ
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Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8JDI
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BU of 8jdi by Molmil
Crystal structure of Cas7-AcrIF25 complex
分子名称: AcrIF25, CRISPR-associated protein Csy3
著者Yang, J, Wang, J, Wang, Y.
登録日2023-05-14
公開日2024-05-29
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.372 Å)
主引用文献An anti-CRISPR that pulls apart a CRISPR-Cas complex.
Nature, 2024
8JCZ
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Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode III)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCY
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Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode I)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCX
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Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode II)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCW
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Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode I)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCV
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BU of 8jcv by Molmil
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode II)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCU
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BU of 8jcu by Molmil
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode I)
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
8JCR
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BU of 8jcr by Molmil
Crystal structure of Procerain from Calotropis gigantea (pH 6.0)
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ...
著者Kumar, A, Jamdar, S.N, Srivastava, G, Makde, R.D.
登録日2023-05-11
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of Procerain from Calotropis gigantea
To Be Published
8JCN
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The crystal structure of SARS-CoV-2 main protease in complex with Compound 58
分子名称: 1-[3-(diphenoxyphosphorylamino)phenyl]ethanone, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ...
著者Zhao, Y, Zhu, Y, Rao, Z.
登録日2023-05-11
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献The crystal structure of SARS-CoV-2 main protease in complex with Compound 58
To Be Published
8JCM
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BU of 8jcm by Molmil
The crystal structure of SARS-CoV-2 main protease in complex with Compound 55
分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, HYDROSULFURIC ACID, ...
著者Zhao, Y, Zhu, Y, Rao, Z.
登録日2023-05-11
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献The crystal structure of SARS-CoV-2 main protease in complex with Compound 55
To Be Published
8JCK
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BU of 8jck by Molmil
The crystal structure of SARS-CoV-2 main protease in complex with Compound 32
分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Zhao, Y, Zhu, Y, Rao, Z.
登録日2023-05-11
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献The crystal structure of SARS-CoV-2 main protease in complex with Compound 32
To Be Published
8JCJ
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BU of 8jcj by Molmil
The crystal structure of SARS-CoV-2 main protease in complex with Compound 18
分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Zhao, Y, Zhu, Y, Rao, Z.
登録日2023-05-11
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of SARS-CoV-2 main protease in complex with Compound 18
To Be Published
8JCA
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BU of 8jca by Molmil
Cyrstal structure of SKIP RUN domain in complex with GTP-bound Arl8b(Q75L)
分子名称: ADP-ribosylation factor-like protein 8B, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Qiu, X.H, Pan, L.F.
登録日2023-05-10
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mechanistic Insights into the Interactions of Arl8b with the RUN Domains of PLEKHM1 and SKIP.
J.Mol.Biol., 435, 2023
8JC5
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Crystal structure of PLEKHM1 RUN domain in complex with GTP-bound Arl8b(Q75L)
分子名称: ADP-ribosylation factor-like protein 8B, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Qiu, X.H, Pan, L.F.
登録日2023-05-10
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Mechanistic Insights into the Interactions of Arl8b with the RUN Domains of PLEKHM1 and SKIP.
J.Mol.Biol., 435, 2023
8JBR
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BU of 8jbr by Molmil
Structure of McyA2-CAPCP
分子名称: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, McyA protein
著者Peng, Y.J.
登録日2023-05-09
公開日2024-01-24
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Modular catalytic activity of nonribosomal peptide synthetases depends on the dynamic interaction between adenylation and condensation domains.
Structure, 32, 2024
8JBP
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BU of 8jbp by Molmil
Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57
分子名称: ARSENIC, Triosephosphate isomerase
著者Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K.
登録日2023-05-09
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
8JBO
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Crystal structure of TxGH116 from Thermoanaerobacterium xylanolyticum with isofagomine
分子名称: 1,2-ETHANEDIOL, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, CALCIUM ION, ...
著者Pengthaisong, S, Ketudat Cairns, J.R.
登録日2023-05-09
公開日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for inhibition of a GH116 beta-glucosidase and its missense mutants by GBA2 inhibitors: Crystallographic and quantum chemical study.
Chem.Biol.Interact., 384, 2023
8JBM
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Crystal structure of Na+,K+-ATPase in the E1.Mn2+ state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C.
登録日2023-05-09
公開日2023-08-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate.
Febs Lett., 597, 2023
8JBL
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Crystal structure of Na+,K+-ATPase in the E1.Mg2+ state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C.
登録日2023-05-09
公開日2023-08-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate.
Febs Lett., 597, 2023
8JBK
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Crystal structure of Na+,K+-ATPase in the E1.3Na+ state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C.
登録日2023-05-09
公開日2023-08-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate.
Febs Lett., 597, 2023
8JBA
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Discovery and Crystallography Study of Novel Oxadiazole Analogs as Small Molecule PD-1/PD-L1 inhibitors
分子名称: (2~{S})-2-[[3-[[5-[(2-methyl-3-phenyl-phenoxy)methyl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]methylamino]-3-oxidanyl-propanoic acid, Programmed cell death 1 ligand 1
著者Cheng, Y, Xiao, Y.B.
登録日2023-05-08
公開日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery and Crystallography Study of Novel Biphenyl Ether and Oxadiazole Thioether (Non-Arylmethylamine)-Based Small-Molecule PD-1/PD-L1 Inhibitors as Immunotherapeutic Agents.
J.Med.Chem., 66, 2023

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件を2024-08-07に公開中

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