PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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6PH6	Ternary complex crystal structure of DNA polymerase Beta with 2nt-gap with dCTP bound downstream 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*G)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-06-25 公開日 2019-12-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 DNA polymerase beta nucleotide-stabilized template misalignment fidelity depends on local sequence context. J.Biol.Chem., 295, 2020
4XDU	Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein,a bifunctional FMN transferase/FAD pyrophosphatase, N55Y mutant, ADP bound form 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. 登録日 2014-12-20 公開日 2015-10-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein. Mbio, 6, 2015
6EXK	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - unfolded HTH motif 分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, SODIUM ION, ... 著者 Hall, M, Grundstrom, C, Begum, A, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-11-08 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
3IQF	Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methenyl-tetrahydromethanopterin 分子名称: 1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol, CALCIUM ION, F420-dependent methylenetetrahydromethanopterin dehydrogenase, ... 著者 Ceh, K.E, Demmer, U, Warkentin, E, Moll, J, Thauer, R.K, Shima, S, Ermler, U. 登録日 2009-08-20 公開日 2009-10-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of the hydride transfer mechanism in F(420)-dependent methylenetetrahydromethanopterin dehydrogenase Biochemistry, 48, 2009
6OZF	Crystal structure of Thermotoga maritima (Tm) Endonuclease V (D110N) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA/RNA (5'-D(P*AP*AP*TP*GP*I)-R(P*A)-D(P*GP*AP*TP*GP*CP*T)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
4XLC	Tailspike protein double mutant D339N/E372A of E. coli bacteriophage HK620 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... 著者 Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. 登録日 2015-01-13 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein. to be published
4XN9	Crystal Structure of E. coli Aminopeptidase N in complex with Beta Alanine 分子名称: Aminopeptidase N, BETA-ALANINE, MALONATE ION, ... 著者 Addlagatta, A, Gumpena, R. 登録日 2015-01-15 公開日 2016-03-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of E. coli Aminopeptidase N in complex with Beta Alanine To Be Published
3IVU	Homocitrate Synthase Lys4 bound to 2-OG 分子名称: 2-OXOGLUTARIC ACID, COBALT (II) ION, Homocitrate synthase, ... 著者 Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. 登録日 2009-09-01 公開日 2009-09-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
6MP3	Binary structure of DNA polymerase eta in complex with templating hypoxanthine 分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*IP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... 著者 Hawkins, M.A, Jung, H, Lee, S. 登録日 2018-10-05 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.907 Å) 主引用文献 Structural Analysis of Translesion Synthesis Across Hypoxanthine Lesion Using Human DNA Polymerase Eta To Be Published
3IVT	Homocitrate Synthase Lys4 bound to 2-OG 分子名称: 2-OXOGLUTARIC ACID, Homocitrate synthase, mitochondrial, ... 著者 Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. 登録日 2009-09-01 公開日 2009-09-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
4Z79	Leiomodin-1 Actin-Binding Site 2 (ABS2) 分子名称: CHLORIDE ION, GLYCEROL, Leiomodin-1 Actin-Binding Site 2 (ABS2), ... 著者 Rebowski, G, Boczkowska, M, Dominguez, R. 登録日 2015-04-06 公開日 2015-10-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 How Leiomodin and Tropomodulin use a common fold for different actin assembly functions. Nat Commun, 6, 2015
6MOZ	Structure of acid-beta-glucosidase in complex with an aromatic pyrrolidine iminosugar inhibitor 分子名称: (2R,3S,4R)-2-{[4-(3,5-dichlorophenyl)-1H-1,2,3-triazol-1-yl]methyl}pyrrolidine-3,4-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Patterson-Orazem, A.C, Lieberman, R.L. 登録日 2018-10-05 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of beta-glucocerebrosidase inhibition. Bioorg.Chem., 86, 2019
2JHN	3-methyladenine dna-glycosylase from Archaeoglobus fulgidus 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-METHYLADENINE DNA-GLYCOSYLASE, GLYCEROL, ... 著者 Leiros, I, Nabong, M.P, Grosvik, K, Ringvoll, J, Haugland, G.T, Uldal, L, Reite, K, Olsbu, I.K, Knaevelsrud, I, Moe, E, Andersen, O.A, Birkeland, N.K, Ruoff, P, Klungland, A, Bjelland, S. 登録日 2007-02-22 公開日 2007-04-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA Embo J., 26, 2007
3J6B	Structure of the yeast mitochondrial large ribosomal subunit 分子名称: 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... 著者 Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. 登録日 2014-01-22 公開日 2014-04-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the yeast mitochondrial large ribosomal subunit. Science, 343, 2014
6PH5	Binary product complex crystal structure of DNA polymerase Beta with an extra-helical template base 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-06-25 公開日 2019-12-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 DNA polymerase beta nucleotide-stabilized template misalignment fidelity depends on local sequence context. J.Biol.Chem., 295, 2020
3JR7	The crystal structure of the protein of DegV family COG1307 with unknown function from Ruminococcus gnavus ATCC 29149 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, PHOSPHATE ION, SODIUM ION, ... 著者 Zhang, R, Hatzos, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-09-08 公開日 2009-10-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of the protein of DegV family COG1307 with unknown function from Ruminococcus gnavus ATCC 29149 To be Published
6N6K	Human REXO2 bound to pAG 分子名称: MALONATE ION, RNA (5'-R(P*AP*G)-3'), RNA exonuclease 2 homolog,Small fragment nuclease, ... 著者 Lormand, J.D, Sondermann, H. 登録日 2018-11-26 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.418 Å) 主引用文献 A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation. Elife, 8, 2019
6MSX	Iron containing ferritin at 1.43A 分子名称: 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... 著者 Blackburn, A, Partowmah, S.H, Brennan, H.M, Mestizo, K.E, Stivala, C.D, Petreczky, J, Perez, A, Horn, A, McSweeney, S. 登録日 2018-10-18 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 A simple technique to improve microcrystals using gel exclusion of nucleation inducing elements To Be Published
6FHN	Structural dynamics and catalytic properties of a multi-modular xanthanase (Pt derivative) 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Moroz, O.V, Jensen, P.F, McDonald, S.P, McGregor, N, Blagova, E, Comamala, G, Segura, D.R, Anderson, L, Vasu, S.M, Rao, V.P, Giger, L, Monrad, R.N, Svendsen, A, Nielsen, J.E, Henrissat, B, Davies, G.J, Brumer, H, Rand, K, Wilson, K.S. 登録日 2018-01-15 公開日 2018-08-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase Acs Catalysis, 2018
6MPY	B. pseudomallei KatG crystallized in the presence of benzoyl hydrazide 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Catalase-peroxidase, ... 著者 Loewen, P.C. 登録日 2018-10-09 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 B. pseudomallei KatG crystallized in the presence of benzoyl hydrazide To be published
6MZ1	CTX-M-14 Class A Beta-Lactamase in Complex with Avibactam at pH 5.3 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, PHOSPHATE ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-11-03 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Mechanism of proton transfer in class A beta-lactamase catalysis and inhibition by avibactam. Proc.Natl.Acad.Sci.USA, 117, 2020
6FHJ	Structural dynamics and catalytic properties of a multi-modular xanthanase, native. 分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Moroz, O.V, Jensen, P.F, McDonald, S.P, McGregor, N, Blagova, E, Comamala, G, Segura, D.R, Anderson, L, Vasu, S.M, Rao, V.P, Giger, L, Monrad, R.N, Svendsen, A, Nielsen, J.E, Henrissat, B, Davies, G.J, Brumer, H, Rand, K, Wilson, K.S. 登録日 2018-01-14 公開日 2018-08-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase Acs Catalysis, 2018
3JPR	Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dimethyl methylene triphosphate 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(1-methyl-1-phosphonoethyl)phosphoryl]oxy}phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... 著者 Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E. 登録日 2009-09-04 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues. J.Am.Chem.Soc., 132, 2010
6PKZ	Structure of human DNA polymerase beta N279A complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2019-06-30 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structure of human DNA polymerase beta N279A complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP To Be Published
6N2R	Binary complex crystal structure of DNA polymerase Beta with 5-carboxy-dC (5-caC) at the templating position 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(1CC)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-11-14 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA polymerase beta. J.Biol.Chem., 294, 2019

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